theobromine has been researched along with Coronary Disease in 15 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of the haemorrheological agent pentoxifylline was investigated in a canine model of acute myocardial infarction, induced by occlusion of the left anterior descending coronary for 6 h." | 7.67 | Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction. ( Campbell, CA; Clavenna, CF; Kloner, RA; Wynne, J, 1988) |
| " The effect of the haemorrheological agent pentoxifylline was investigated in a canine model of acute myocardial infarction, induced by occlusion of the left anterior descending coronary for 6 h." | 3.67 | Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction. ( Campbell, CA; Clavenna, CF; Kloner, RA; Wynne, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DE MAURO, A | 1 |
| ROSSI, A | 1 |
| FUKUDA, H | 1 |
| STERN, ML | 1 |
| Gallenkämper, W | 1 |
| Rücker, W | 1 |
| Schrör, K | 1 |
| Nobbe, F | 1 |
| Kobaladze, SG | 1 |
| Brown, KA | 1 |
| Slinker, BK | 1 |
| Campbell, CA | 1 |
| Clavenna, CF | 1 |
| Wynne, J | 1 |
| Kloner, RA | 1 |
| Insel, J | 1 |
| Halle, AA | 1 |
| Mirvis, DM | 1 |
| Loyd, RG | 1 |
| Prian, GW | 1 |
| Gomez, H | 1 |
| Laub, J | 1 |
| Mertz, GH | 1 |
| Badalian, GO | 1 |
| Episkoposian, NG | 1 |
| Amatuni, GV | 1 |
| Iunusov, RA | 1 |
| Burykh, LN | 1 |
| Sviridova, NI | 1 |
| Atroshchenko, ES | 1 |
| Alberto, S | 2 |
| Brusasco, L | 2 |
| Colongo, PG | 2 |
1 review available for theobromine and Coronary Disease
| Article | Year |
|---|---|
Clinical considerations and treatment of diabetic angiopathy.
Topics: Adult; Arterial Occlusive Diseases; Coronary Disease; Diabetic Angiopathies; Humans; Intermittent Cl | 1979 |
14 other studies available for theobromine and Coronary Disease
| Article | Year |
|---|---|
[Therapeutic activity of a new hydrosoluble derivative of theobromine: 1-(beta-hydroxypropyl)-theobromine and its compounds].
Topics: Coronary Disease; Diuretics; Heart Failure; Humans; Intracranial Arteriosclerosis; Theobromine | 1961 |
[STUDIES ON THE SYNTHESES OF XANTHINE DERIVATIVES. V. SYNTHESES OF SOME 7-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOPHYLINE AND 1-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOBROMINE AND THEIR DERIVATIVES].
Topics: Chemistry, Pharmaceutical; Coronary Disease; Pharmacology; Pharmacy; Pregnenes; Research; Theobromin | 1963 |
PREVENTION OF CORONARY THROMBOSIS: CLINICAL OBSERVATIONS FOR 1 TO 10 YEARS.
Topics: Biomedical Research; Coronary Disease; Coronary Thrombosis; Drug Therapy; Humans; Niacin; Nicotinic | 1965 |
Cardioprotective actions of pentoxifylline in an animal model of acute myocardial ischaemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cathepsin D; Cathepsins; Cats; Coronary Disease; Creatine Kin | 1984 |
On the effect of pentoxifylline in ischemic heart disease.
Topics: Adult; Aged; Blood Viscosity; Coronary Circulation; Coronary Disease; Erythrocytes; Female; Humans; | 1978 |
Pentoxifylline (Trental) does not inhibit dipyridamole-induced coronary hyperemia: implications for dipyridamole-thallium-201 myocardial imaging.
Topics: Animals; Coronary Circulation; Coronary Disease; Dipyridamole; Dogs; Female; Hyperemia; Male; Pentox | 1990 |
Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction.
Topics: Animals; Blood Pressure; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Heart Rat | 1988 |
Efficacy of pentoxifylline in patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Viscosity; Coronary Disease; Electrocardiography; Exercise Test; | 1988 |
Failure of pentoxifylline for end-stage peripheral vascular disease.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Coronary Disease; Humans; Intermittent Claudic | 1987 |
[Effect of fructose-1,6-diphosphate and trental on the erythrocyte aggregating capacity in ischemic heart disease].
Topics: Adult; Aged; Alcian Blue; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug | 1987 |
[Hemodynamic assessment of anti-angina preparations in treating patients with ischemic heart disease with hypertension].
Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Hum | 1987 |
[Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients].
Topics: Adult; Capillary Permeability; Chronic Disease; Coronary Disease; Hemodynamics; Humans; Leg; Lymph; | 1985 |
The use of a compound of adenosine triphosphate (ATP), cocarboxylase and beta-hydroxypropyl-theobromine in cardiovascular therapy.
Topics: Adenosine Triphosphate; Adult; Aged; Coronary Disease; Female; Heart Failure; Humans; Male; Middle A | 1966 |
[On the use of an association of ATP, cocarboxylase and beta-hydroxy-propyl-theobromine in cardiovascular therapy].
Topics: Adenosine Triphosphate; Adult; Aged; Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Femal | 1966 |