theobromine has been researched along with Chronic Illness in 26 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of pentoxifylline on intermittent claudication were evaluated at a dose of 1200 mg/day in an open-label twelve-week study on geriatric patients with chronic occlusive arterial disease (COAD)." | 9.06 | Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication. ( Cobert, BL; Cohn, JB; Crowder, JE; Hryniewicki, SW; Morgan, DL; Piccirillo, RT; Savitsky, JP; Slywka, J; Wilcox, CS, 1989) |
| "Ten patients with Stage II chronic arterial occlusive disease (intermittent claudication) took part in a randomized, intraindividual crossover study involving acute intravenous administration of 200 mg pentoxifylline or physiological saline solution (placebo)." | 9.06 | Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise. ( Ehrly, AM; Saeger-Lorenz, K, 1987) |
| "A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months." | 7.68 | Treatment of sickle cell leg ulcers with pentoxifylline. ( Frost, ML; Treadwell, P, 1990) |
| "The effects of pentoxifylline on intermittent claudication were evaluated at a dose of 1200 mg/day in an open-label twelve-week study on geriatric patients with chronic occlusive arterial disease (COAD)." | 5.06 | Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication. ( Cobert, BL; Cohn, JB; Crowder, JE; Hryniewicki, SW; Morgan, DL; Piccirillo, RT; Savitsky, JP; Slywka, J; Wilcox, CS, 1989) |
| "Ten patients with Stage II chronic arterial occlusive disease (intermittent claudication) took part in a randomized, intraindividual crossover study involving acute intravenous administration of 200 mg pentoxifylline or physiological saline solution (placebo)." | 5.06 | Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise. ( Ehrly, AM; Saeger-Lorenz, K, 1987) |
| "A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months." | 3.68 | Treatment of sickle cell leg ulcers with pentoxifylline. ( Frost, ML; Treadwell, P, 1990) |
| "The effect of combined use of pentoxifylline and solcoseryl was studied in 35 patients with chronic pancreatitis." | 3.67 | [Trial of the combined use of trental and solcoseryl in treating patients with chronic pancreatitis]. ( Solov'eva, NE; Trusov, VV; Vakhrushev, IaM, 1988) |
| "Pentoxifylline was administered orally at a dose of 1200 mg/day over a period of 30 days (eight patients) or by intravenous infusion of 100 ml saline containing 400 mg of the drug in 1 hour (three patients)." | 1.26 | Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease. ( Battistini, N; Nardini, M; Passero, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (96.15) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilla, G | 1 |
| Ciaponi, A | 1 |
| Migliavacca, A | 1 |
| Bonora, C | 1 |
| Angelkort, B | 4 |
| Kiesewetter, H | 1 |
| Accetto, B | 1 |
| Porter, JM | 1 |
| Cutler, BS | 1 |
| Lee, BY | 1 |
| Reich, T | 1 |
| Reichle, FA | 1 |
| Scogin, JT | 1 |
| Strandness, DE | 1 |
| Shtok, VN | 1 |
| Fedorova, NV | 1 |
| Gadanova, IV | 1 |
| Passero, S | 1 |
| Nardini, M | 1 |
| Battistini, N | 1 |
| Harwart, D | 1 |
| Koppenhagen, K | 1 |
| Wenig, HG | 1 |
| Gerzić, Z | 1 |
| Dukić, V | 1 |
| Milicević, M | 1 |
| Doppelfeld, E | 1 |
| d'Ottilie, H | 1 |
| Dornbusch, R | 1 |
| Adams, HJ | 1 |
| Störmer, B | 1 |
| Kleinschmidt, K | 1 |
| Loose, D | 1 |
| Kremer, K | 1 |
| Tannenberg, G | 1 |
| Frost, ML | 1 |
| Treadwell, P | 1 |
| Crowder, JE | 1 |
| Cohn, JB | 1 |
| Savitsky, JP | 1 |
| Morgan, DL | 1 |
| Slywka, J | 1 |
| Cobert, BL | 1 |
| Hryniewicki, SW | 1 |
| Piccirillo, RT | 1 |
| Wilcox, CS | 1 |
| Trübestein, G | 1 |
| von Bary, S | 1 |
| Breddin, K | 1 |
| Diehm, C | 1 |
| Gruss, JD | 1 |
| Heinrich, H | 1 |
| Horsch, S | 1 |
| Kriessmann, A | 1 |
| Maass, U | 1 |
| Martin, M | 1 |
| Nazarova, KhI | 1 |
| Hartmann, A | 1 |
| Tsuda, Y | 1 |
| Vakhrushev, IaM | 1 |
| Trusov, VV | 1 |
| Solov'eva, NE | 1 |
| Ehrly, AM | 1 |
| Saeger-Lorenz, K | 1 |
| Shoĭkhet, IN | 1 |
| Treĭvish, VS | 1 |
| Novikova, NN | 1 |
| Atroshchenko, ES | 1 |
| Dvorkin, SB | 1 |
| Chernookiĭ, GP | 1 |
| Nuzov, BG | 1 |
1 review available for theobromine and Chronic Illness
| Article | Year |
|---|---|
[Blood rheology in peripheral occlusive disease. Effects of hemodilution and pentoxifylline].
Topics: Arterial Occlusive Diseases; Chronic Disease; Combined Modality Therapy; Hemodilution; Humans; Pento | 1986 |
9 trials available for theobromine and Chronic Illness
| Article | Year |
|---|---|
Beneficial hemorheologic therapy of chronic peripheral arterial disorders with pentoxifylline: results of double-blind study versus vasodilator-nylidrin.
Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blind Me | 1982 |
Pentoxifylline efficacy in the treatment of intermittent claudication: multicenter controlled double-blind trial with objective assessment of chronic occlusive arterial disease patients.
Topics: Aged; Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; E | 1982 |
The treatment of chronic cerebrovascular insufficiency. A double-blind study with pentoxifylline ('Trental' 400).
Topics: Administration, Oral; Aged; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; Do | 1979 |
[The effect of pentoxifylline on liver perfusion: a comparative study in patients with liver diseases and in normal subjects, using 198Au-colloid-scintigraphy (author's transl)].
Topics: Adult; Aged; Chronic Disease; Female; Hepatitis; Humans; Liver; Liver Circulation; Liver Cirrhosis; | 1979 |
[Therapy of chronic bronchitis. Results of a field study with Brondiletten retard].
Topics: Aged; Benactyzine; Bronchitis; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparation | 1976 |
Efficacy and safety of pentoxifylline in geriatric patients with intermittent claudication.
Topics: Aged; Arterial Occlusive Diseases; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Electr | 1989 |
Intravenous prostaglandin E1 versus pentoxifylline therapy in chronic arterial occlusive disease--a controlled randomised multicenter study.
Topics: Aged; Alprostadil; Arterial Occlusive Diseases; Chronic Disease; Follow-Up Studies; Humans; Multicen | 1989 |
A controlled study on the effect of pentoxifylline and an ergot alkaloid derivative on regional cerebral blood flow in patients with chronic cerebrovascular disease.
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; E | 1988 |
Influence of pentoxifylline on muscle tissue oxygen tension (pO2) of patients with intermittent claudication before and after pedal ergometer exercise.
Topics: Arterial Occlusive Diseases; Chronic Disease; Clinical Trials as Topic; Exercise Test; Humans; Inter | 1987 |
16 other studies available for theobromine and Chronic Illness
| Article | Year |
|---|---|
[Chronic senile cerebrovascular insufficiency. Effects of suloctidil and pentoxifylline on erythrocyte deformability].
Topics: Cholesterol; Chronic Disease; Erythrocytes; Humans; Intracranial Arteriosclerosis; Pentoxifylline; P | 1983 |
Influence of risk factors and coagulation phenomena on the fluidity of blood in chronic arterial occlusive disease.
Topics: Adenosine Diphosphate; Arterial Occlusive Diseases; Blood Coagulation; Blood Flow Velocity; Chronic | 1981 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease.
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Female; Humans; Male; | 1981 |
[Thrombocytic function, plasmatic blood coagulation and fibrinolysis in chronic arterial occlusive disease. Study with pentoxifilline].
Topics: Adult; Aged; Arterial Occlusive Diseases; Blood Coagulation; Blood Platelets; Chronic Disease; Femal | 1979 |
[Drug therapy of chronic tissue ischemia with improvement of microcirculation].
Topics: Adult; Blood Vessel Prosthesis; Chronic Disease; Extremities; Humans; Ischemia; Ischemic Attack, Tra | 1978 |
[Treatment of chronic arterial occlusive disease. Clinical study with a new galenic preparation of Pentoxifyllin (Trental 400) (author's transl)].
Topics: Aged; Arm; Arterial Occlusive Diseases; Blood Flow Velocity; Chronic Disease; Drug Evaluation; Femal | 1978 |
Rheological changes in the blood of patients with chronic arterial occlusive disease after the administration of vasoactive drugs.
Topics: Arterial Occlusive Diseases; Bencyclane; Blood Viscosity; Chronic Disease; Cycloheptanes; Humans; Pe | 1977 |
[Experiences with Brondiletten retard (B 680 RD) in bronchitic ventilation disorders].
Topics: Adult; Benactyzine; Bronchitis; Bronchodilator Agents; Chronic Disease; Delayed-Action Preparations; | 1975 |
Treatment of sickle cell leg ulcers with pentoxifylline.
Topics: Anemia, Sickle Cell; Chronic Disease; Humans; Leg Ulcer; Male; Middle Aged; Pentoxifylline; Recurren | 1990 |
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet | 1988 |
[Trial of the combined use of trental and solcoseryl in treating patients with chronic pancreatitis].
Topics: Actihaemyl; Adult; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male | 1988 |
[Pentoxifylline (Trental) in the treatment of chronic glomerulonephritis].
Topics: Adolescent; Adult; Chronic Disease; Drug Evaluation; Female; Glomerulonephritis; Humans; Hypertensio | 1986 |
[Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients].
Topics: Adult; Capillary Permeability; Chronic Disease; Coronary Disease; Hemodynamics; Humans; Leg; Lymph; | 1985 |
[Conservative treatment of trophic leg ulcers with trental].
Topics: Adult; Aged; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Pentoxifylline; Th | 1985 |
[Use of teonikol and trental in the combined treatment of patients with suppurative surgical infection and concomitant diabetes mellitus].
Topics: Chronic Disease; Conjunctiva; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemodynamics; Hu | 1985 |