theobromine has been researched along with Cerebral Ischemia in 17 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 8.82 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Bath, PM; Bath-Hextall, FJ, 2004) |
| "The objective of this review was to assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 8.80 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Asplund, K; Bath, FJ; Bath, PM, 2000) |
| "The effect of pentoxifylline on regional cerebral ischemia was evaluated in 22 cats." | 7.66 | Pentoxifylline in regional cerebral ischemia in cats. ( Michenfelder, JD; Milde, JH; Steen, PA, 1982) |
| "Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder characterized by a brief decline in blood flow, neurological deficits, and is often predictive of stroke." | 5.62 | Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model. ( Bhat, JA; Gupta, S; Kumar, M, 2021) |
| "To assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 4.82 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Bath, PM; Bath-Hextall, FJ, 2004) |
| "The objective of this review was to assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 4.80 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Asplund, K; Bath, FJ; Bath, PM, 2000) |
| "The effect of pentoxifylline on regional cerebral ischemia was evaluated in 22 cats." | 3.66 | Pentoxifylline in regional cerebral ischemia in cats. ( Michenfelder, JD; Milde, JH; Steen, PA, 1982) |
| "Treatment with theobromine significantly attenuated neurological deficits and improved sensorimotor functions and memory in rats with CH." | 1.72 | Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion. ( Bhat, JA; Kumar, M, 2022) |
| "Transient global cerebral ischemia (tGCI) is a cerebrovascular disorder characterized by a brief decline in blood flow, neurological deficits, and is often predictive of stroke." | 1.62 | Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model. ( Bhat, JA; Gupta, S; Kumar, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bhat, JA | 2 |
| Kumar, M | 2 |
| Gupta, S | 1 |
| Bath, PM | 2 |
| Bath-Hextall, FJ | 1 |
| Schneider, R | 2 |
| Schmid-Schönbein, H | 1 |
| Kiesewetter, H | 2 |
| Shtok, VN | 1 |
| Fedorova, NV | 1 |
| Gadanova, IV | 1 |
| Steen, PA | 1 |
| Milde, JH | 1 |
| Michenfelder, JD | 1 |
| Strano, A | 1 |
| Davì, G | 1 |
| Novo, S | 1 |
| Avellone, G | 1 |
| Pinto, A | 1 |
| Muggeo, M | 1 |
| Calabrò, A | 1 |
| Businaro, V | 1 |
| Patussi, L | 1 |
| Volpe, A | 1 |
| Signorini, GP | 1 |
| Crepaldi, G | 1 |
| Barth, A | 1 |
| Newell, DW | 1 |
| Nguyen, LB | 1 |
| Winn, HR | 1 |
| Wender, R | 1 |
| Meno, JR | 1 |
| Janigro, D | 1 |
| Bath, FJ | 1 |
| Asplund, K | 1 |
| Müller, R | 2 |
| Schröer, R | 1 |
| Cohen, MM | 1 |
| Harrison, W | 1 |
| Gray, R | 1 |
| Becker, R | 1 |
| Johansson, BB | 1 |
| Olsson, AL | 1 |
| Ott, E | 1 |
| Körner, E | 1 |
| Lechner, H | 1 |
| Yayá, R | 1 |
| Aznar, J | 1 |
| Vayá, A | 1 |
| Villa, P | 1 |
| Santos, T | 1 |
| Vallés, J | 1 |
| Martinez-Sales, V | 1 |
4 reviews available for theobromine and Cerebral Ischemia
| Article | Year |
|---|---|
Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke.
Topics: Brain Ischemia; Humans; Neuroprotective Agents; Pentoxifylline; Platelet Aggregation Inhibitors; Str | 2004 |
Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke.
Topics: Brain Ischemia; Humans; Neuroprotective Agents; Pentoxifylline; Platelet Aggregation Inhibitors; Str | 2000 |
Pentoxifylline -- a biomedical profile.
Topics: Arterial Occlusive Diseases; Blood Viscosity; Brain Ischemia; Cerebrovascular Circulation; Erythrocy | 1979 |
Cerebrovascular circulatory disorders: new aspects of pathophysiology and therapy.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Edema; Brain Ischemia; Cell Membrane Permeability; Cer | 1979 |
2 trials available for theobromine and Cerebral Ischemia
| Article | Year |
|---|---|
Hemorheologic treatment of cerebral reversible ischemic episodes with pentoxifylline--a prospective study.
Topics: Aged; Blood Circulation; Brain Ischemia; Erythrocyte Deformability; Female; Humans; Male; Middle Age | 1988 |
Effect of dipyridamole plus pentoxifylline in patients with diffuse cerebrovascular insufficiency.
Topics: Aged; Brain Ischemia; Clinical Trials as Topic; Dipyridamole; Drug Therapy, Combination; Female; Hum | 1985 |
11 other studies available for theobromine and Cerebral Ischemia
| Article | Year |
|---|---|
Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion.
Topics: Acetylcholinesterase; Animals; Brain; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Commo | 2022 |
Neuroprotective effects of theobromine in transient global cerebral ischemia-reperfusion rat model.
Topics: Administration, Oral; Animals; Brain Ischemia; Disease Models, Animal; Female; Glutathione; Ischemic | 2021 |
The rheological efficiency of parenteral pentoxifylline (Trental) in patients with ischemic brain lesions. Preliminary results.
Topics: Adult; Aged; Blood Viscosity; Brain Ischemia; Erythrocyte Aggregation; Erythrocytes; Female; Hematoc | 1983 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
Pentoxifylline in regional cerebral ischemia in cats.
Topics: Animals; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circulation; Female; Male; Pento | 1982 |
[Parenteral pentoxifylline treatment of ischemic cerebrovascular accident. Preliminary results].
Topics: Aged; Blood Viscosity; Brain Ischemia; Erythrocyte Aggregation; Female; Hematocrit; Humans; Infusion | 1982 |
[Clinical evaluation of the effects of pentoxifylline in patients with chronic peripheral circulatory disorders].
Topics: Aged; Arteriosclerosis Obliterans; Blood Pressure; Blood Viscosity; Brain Ischemia; Drug Evaluation; | 1981 |
[Hemocoagulation, fibrinolytic and rheologic parameters in ischemic vasculopathy. Effects of pentoxifylline in the treatment of acute cerebral vasculopathy].
Topics: Acute Disease; Blood Coagulation; Brain Ischemia; Drug Evaluation; Female; Fibrinogen; Fibrinolysis; | 1981 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Br | 1997 |
The effect of pentoxifylline on cerebral ischemia and amino acid incorporation into gerbil brain.
Topics: Amino Acids; Animals; Brain; Brain Ischemia; Gerbillinae; Pentoxifylline; Theobromine | 1979 |
Pentoxifylline does not reduce cerebral ischemic edema in hypertensive rats.
Topics: Animals; Brain Edema; Brain Ischemia; Male; Pentoxifylline; Rats; Rats, Inbred SHR; Theobromine | 1989 |