Page last updated: 2024-11-05

theobromine and Cerebral Arteriosclerosis

theobromine has been researched along with Cerebral Arteriosclerosis in 14 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Research Excerpts

ExcerptRelevanceReference
"Twenty outpatients (8 women and 12 men; age range 52-66 years) with mild to moderate degree of cerebrovascular disorders and arteriosclerotic dementia, were randomly assigned to either control or pentoxifylline group (400 mg X 3/day/4 weeks p."5.05Cerebral blood flow in patients with cerebrovascular disorders: study with pentoxifylline. ( Hartmann, A, 1981)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199014 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DE MAURO, A1
ROSSI, A1
SPERLING, R1
FELSTEIN, IL1
BJURWILL, B1
WALDRON, DH1
MUSTARD, DM1
DUCHENE, W1
Pilla, G1
Ciaponi, A1
Migliavacca, A1
Bonora, C1
Hartmann, A1
Feruglio, FS1
Ponte, E1
Feine-Haake, G1
Dzialek, E1
Orzechowska-Wolczyk, M1
Zawadzki, Z1
Köhler, W1

Trials

2 trials available for theobromine and Cerebral Arteriosclerosis

ArticleYear
Cerebral blood flow in patients with cerebrovascular disorders: study with pentoxifylline.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Aged; Cerebrovascular Circulation; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Mi

1981
[Assessment of the therapeutic effect of Trental 400. Double-blind study in geriatric patients with circulatory disorders].
    Fortschritte der Medizin, 1977, Jan-06, Volume: 95, Issue:1

    Topics: Aged; Blood Circulation; Extremities; Female; Humans; Intracranial Arteriosclerosis; Long-Term Care;

1977

Other Studies

12 other studies available for theobromine and Cerebral Arteriosclerosis

ArticleYear
[Therapeutic activity of a new hydrosoluble derivative of theobromine: 1-(beta-hydroxypropyl)-theobromine and its compounds].
    Minerva cardioangiologica, 1961, Volume: 9

    Topics: Coronary Disease; Diuretics; Heart Failure; Humans; Intracranial Arteriosclerosis; Theobromine

1961
[Treatment of cerebral arteriosclerosis with cosaldon].
    Medizinische Klinik, 1960, May-06, Volume: 55

    Topics: Drug Combinations; Humans; Intracranial Arteriosclerosis; Nicotinic Acids; Theobromine; Vasodilator

1960
The value of cosaldon in cerebral arteriosclerosis.
    The British journal of clinical practice, 1963, Aug-08, Volume: 17

    Topics: Drug Combinations; Humans; Intracranial Arteriosclerosis; Nicotinic Acids; Theobromine; Vasodilator

1963
[Effect of Cosaldin the capacity for orientation, memory and thinking in elderly patients with cerebral arteriosclerosis].
    Svenska lakartidningen, 1963, Jan-17, Volume: 60

    Topics: Aged; Humans; Intracranial Arteriosclerosis; Memory; Niacin; Nicotinic Acids; Theobromine; Thinking

1963
A REPORT ON THE USE OF COSALDON IN GENERAL PRACTICE.
    The British journal of clinical practice, 1963, Volume: 17

    Topics: Drug Combinations; General Practice; Geriatrics; Intracranial Arteriosclerosis; Nicotinic Acids; The

1963
TREATMENT OF PARKINSONISM IN ELDERLY PATIENTS WITH COSALDON.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Cerebrovascular Circulation; Drug Combinations; Drug Therapy; Geriatrics; Intracranial Arteriosclero

1964
[REPORT ON THE SUBJECT OF RESULTS OBTAINED WITH COSALDON TREATMENT IN 35 PATIENTS OF THE INSTITUT NOTRE-DAME AT BRUGES-ST. MICHEL DURING THE PERIOD FROM JUNE TO DECEMBER, 1963].
    Le Scalpel, 1964, Oct-17, Volume: 117

    Topics: Belgium; Drug Combinations; Drug Therapy; Enkephalin, Methionine; Geriatrics; Hallucinations; Humans

1964
[Chronic senile cerebrovascular insufficiency. Effects of suloctidil and pentoxifylline on erythrocyte deformability].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Cholesterol; Chronic Disease; Erythrocytes; Humans; Intracranial Arteriosclerosis; Pentoxifylline; P

1983
[Clinical aspects of hemorrheology in the aged: possibility of prevention and therapy].
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Aged; Arterial Occlusive Diseases; Female; Humans; Intracranial Arteriosclerosis; Leg; Male; Middle

1981
[Cosaldon in the treatment of cerebral arteriosclerosis].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1975, Sep-15, Volume: 28, Issue:18

    Topics: Adult; Aged; Drug Combinations; Drug Evaluation; Female; Humans; Intracranial Arteriosclerosis; Male

1975
[Experimental investigations on drug induced improvement of brain metabolism].
    Wiener klinische Wochenschrift, 1972, May-26, Volume: 84, Issue:21

    Topics: Adult; Aged; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Epilepsy; Humans; Intellectual

1972
[Cosaldon opens blood-brain barrier].
    Zeitschrift fur Allgemeinmedizin, 1971, Sep-10, Volume: 47, Issue:25

    Topics: Blood-Brain Barrier; Drug Synergism; Humans; Intracranial Arteriosclerosis; Nicotinic Acids; Parkins

1971