Page last updated: 2024-11-05

theobromine and Caries, Dental

theobromine has been researched along with Caries, Dental in 5 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Research Excerpts

ExcerptRelevanceReference
"Theobromine (TB) has been reported to promote tooth remineralization, strengthen tooth substance, and relieve dentin hypersensitivity."1.91Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler. ( Burrow, MF; Hotta, M; Ichimura, Y; Ikeda, M; Kitada, N; Kusakabe, S; Nikaido, T; Shimizu, S; Takagaki, T; Toyama, M; Yamamoto, K, 2023)
"Early carious lesions were created in 272 bovine enamel specimens and assigned to sixteen groups (n=17) based on Knoop surface microhardness (SMH)."1.56The effect of theobromine on the in vitro de- and remineralization of enamel carious lesions. ( Eckert, GJ; Levon, JA; Lin, WS; Lippert, F; Morton, D; Thorn, AK, 2020)
"F+theobromine was similar to F."1.46The effects of fluoride, strontium, theobromine and their combinations on caries lesion rehardening and fluoridation. ( Lippert, F, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Shimizu, S2
Kusakabe, S2
Toyama, M2
Takagaki, T2
Kitada, N2
Yamamoto, K2
Ikeda, M2
Ichimura, Y2
Burrow, MF2
Hotta, M2
Nikaido, T2
Nassar, HM1
Lippert, F3
Thorn, AK1
Lin, WS1
Levon, JA1
Morton, D1
Eckert, GJ1
Amaechi, BT1
Porteous, N1
Ramalingam, K1
Mensinkai, PK1
Ccahuana Vasquez, RA1
Sadeghpour, A1
Nakamoto, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effectiveness Evaluation of the Theobromine Containing Toothpastes in Controlling Dental Plaque in Children Aged 6-9years(Randomized Controlled Clinical Trial)[NCT05187507]80 participants (Actual)Interventional2021-09-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for theobromine and Caries, Dental

ArticleYear
Remineralization of artificial enamel lesions by theobromine.
    Caries research, 2013, Volume: 47, Issue:5

    Topics: Calcium; Cariostatic Agents; Dental Caries; Dental Enamel; Electron Probe Microanalysis; Hardness; H

2013

Other Studies

4 other studies available for theobromine and Caries, Dental

ArticleYear
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
    Dental materials journal, 2023, Jan-31, Volume: 42, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine

2023
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
    Dental materials journal, 2023, Jan-31, Volume: 42, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine

2023
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
    Dental materials journal, 2023, Jan-31, Volume: 42, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine

2023
Bacterial adhesion and antibacterial property of coating materials containing theobromine and S-PRG filler.
    Dental materials journal, 2023, Jan-31, Volume: 42, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Dental Caries; Glass Ionomer Cements; Humans; Theobromine

2023
Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol.
    Molecules (Basel, Switzerland), 2021, Jan-08, Volume: 26, Issue:2

    Topics: Animals; Bronchodilator Agents; Cattle; Dental Caries; Dental Enamel; Fluorides; Theobromine; Tooth;

2021
The effect of theobromine on the in vitro de- and remineralization of enamel carious lesions.
    Journal of dentistry, 2020, Volume: 103S

    Topics: Animals; Cariostatic Agents; Cattle; Dental Caries; Dental Enamel; Fluorides; Hardness; Humans; Hydr

2020
The effects of fluoride, strontium, theobromine and their combinations on caries lesion rehardening and fluoridation.
    Archives of oral biology, 2017, Volume: 80

    Topics: Dental Caries; Drug Synergism; Fluoridation; Fluorides; Hardness Tests; Humans; Hydrogen-Ion Concent

2017