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theobromine and Carcinoma, Ehrlich Tumor

theobromine has been researched along with Carcinoma, Ehrlich Tumor in 6 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.

Research Excerpts

ExcerptRelevanceReference
" The influence of the combination of theobromine or pentoxifylline with ADR on the lipid peroxide level (indicating the ADR-induced side effect) and on DNA biosynthesis (indicating the side effect and antitumor activity) were examined."1.30[Effects of methylxanthine derivatives on antitumor activity and toxic side effect of adriamycin induced by inhibition of DNA biosynthesis]. ( Hirota, S; Iwazaki, A; Sadzuka, Y, 1998)
" In the present experiment pentoxifylline appears to be a highly effective platelet aggregation inhibitor: a dose-response curve is apparent in monkey between 6 and 24 mg/kg i."1.26Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis. ( Ambrus, CM; Ambrus, JL; Gastpar, H, 1981)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HENDERSON, JF1
MAZEL, P1
Ambrus, JL2
Ambrus, CM2
Gastpar, H2
Sadzuka, Y3
Iwazaki, A2
Miyagishima, A1
Nozawa, Y1
Hirota, S2
Sugiyama, T1
Sonobe, T1

Other Studies

6 other studies available for theobromine and Carcinoma, Ehrlich Tumor

ArticleYear
DEMETHYLATION OF PURINE ANALOGS BY MICROSOMAL ENZYMES FROM MOUSE LIVER.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Antimetabolites; Caffeine; Carcinoma; Carcinoma, Ehrlich Tumor; Liver; Mercaptopurine; Meta

1964
Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis.
    La Ricerca in clinica e in laboratorio, 1981, Volume: 11 Suppl 1

    Topics: Adenocarcinoma; Adenosine Diphosphate; Animals; Carcinoma, Ehrlich Tumor; Female; Head and Neck Neop

1981
Effects of methylxanthine derivatives on adriamycin concentration and antitumor activity.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:6

    Topics: Animals; Caffeine; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Synergism; Male; Mice; Pentoxifylline

1995
[Effects of methylxanthine derivatives on antitumor activity and toxic side effect of adriamycin induced by inhibition of DNA biosynthesis].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1998, Volume: 118, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Depression, C

1998
Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.
    Toxicology letters, 2000, Apr-03, Volume: 114, Issue:1-3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Bind

2000
Studies on platelet aggregation in vivo. VII: Effect of pentoxyfylline on circulating tumor cells.
    Journal of medicine, 1978, Volume: 9, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Mice; Neoplastic Cells, Circulating; Pentoxifylline; Platelet Agg

1978