theobromine and Brain Vascular Disorders
theobromine has been researched along with Brain Vascular Disorders in 31 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Pentoxifylline is a drug known to increase red cell deformability, thus allowing the 7- to 8-micrometers diameter red cell to flow through the narrowest capillaries of 3-5 micrometers diameter." | 2.36 | Pentoxifylline and cerebrovascular diseases. ( George, C; Marcel, GA, 1983) |
"Pentoxifylline was administered orally at a dose of 1200 mg/day over a period of 30 days (eight patients) or by intravenous infusion of 100 ml saline containing 400 mg of the drug in 1 hour (three patients)." | 1.26 | Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease. ( Battistini, N; Nardini, M; Passero, S, 1981) |
Research
Studies (31)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (93.55) | 18.7374 |
1990's | 2 (6.45) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
COOPER, AJ | 1 |
Martin, P | 1 |
Vives, P | 1 |
Hartmann, A | 4 |
Beyreder, J | 1 |
Marcel, GA | 1 |
George, C | 1 |
Szobor, A | 1 |
Klein, M | 1 |
Bräuer, H | 1 |
Ott, E | 4 |
Lechner, H | 3 |
Fazekas, F | 1 |
Müller, R | 2 |
Lehrach, F | 2 |
Shtok, VN | 1 |
Fedorova, NV | 1 |
Gadanova, IV | 1 |
Passero, S | 1 |
Nardini, M | 1 |
Battistini, N | 1 |
Harwart, D | 1 |
Koeppen, G | 1 |
Schmidt-Modrow, G | 1 |
Ueda, N | 1 |
Muteki, T | 1 |
Tajiri, M | 1 |
Tayama, F | 1 |
Tsutsumi, Y | 1 |
Watanabe, H | 1 |
Sakanashi, K | 1 |
Yoshitake, K | 1 |
Tessitore, A | 1 |
Barone, A | 1 |
Koppenhagen, K | 1 |
Wenig, HG | 1 |
Müller, K | 1 |
Theis, H | 1 |
Sen, S | 1 |
Chakravarty, A | 1 |
Ritzmann, D | 1 |
Lebedeva, NV | 1 |
Khrapova, EV | 1 |
Chandra, B | 1 |
Bowton, DL | 1 |
Stump, DA | 1 |
Prough, DS | 1 |
Toole, JF | 1 |
Lefkowitz, DS | 1 |
Coker, L | 1 |
Dragunow, M | 1 |
Schneider, R | 1 |
Nazarova, KhI | 1 |
Hsu, CY | 1 |
Norris, JW | 1 |
Hogan, EL | 1 |
Bladin, P | 1 |
Dinsdale, HB | 1 |
Yatsu, FM | 1 |
Earnest, MP | 1 |
Scheinberg, P | 1 |
Caplan, LR | 1 |
Karp, HR | 1 |
Tsuda, Y | 1 |
Eninia, GI | 1 |
Egere, DA | 1 |
Robule, VKh | 1 |
Maĭore, IKh | 1 |
Dreyer, H | 1 |
Keussen, M | 1 |
Wojtek, L | 1 |
Reviews
2 reviews available for theobromine and Brain Vascular Disorders
Article | Year |
---|---|
Pentoxifylline and cerebrovascular diseases.
Topics: Animals; Blood Viscosity; Brain Edema; Cerebrovascular Circulation; Cerebrovascular Disorders; Dogs; | 1983 |
Haemorheology and cerebrovascular disease: multifunctional approach with pentoxifylline.
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Edema; Humans; Oxygen Consumption; Pentoxify | 1981 |
Trials
10 trials available for theobromine and Brain Vascular Disorders
Article | Year |
---|---|
Effect of pentoxifylline on regional cerebral blood flow in patients with cerebral vascular disorders.
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Pentoxifyl | 1983 |
Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency.
Topics: Acute Disease; Benzamides; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Therapy, Combin | 1983 |
[Therapy of chronic cerebrovascular insufficiency. Controlled comparative study of 2 cerebral antihypoxidosis agents].
Topics: Adult; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Dihydroergotoxine; Drug | 1982 |
Effect of pentoxifylline on regional cerebral blood flow in patients with cerebrovascular disease.
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Male; Middle Aged; Pen | 1981 |
The treatment of chronic cerebrovascular insufficiency. A double-blind study with pentoxifylline ('Trental' 400).
Topics: Administration, Oral; Aged; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; Do | 1979 |
Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.
Topics: Adult; Cerebrovascular Disorders; Female; Hemiplegia; Humans; Ischemic Attack, Transient; Male; Moto | 1977 |
[Use of sermion, Cavinton and trental in patients with cerebrovascular disorders].
Topics: Administration, Oral; Adult; Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical | 1990 |
Pentoxifylline in acute nonhemorrhagic stroke. A randomized, placebo-controlled double-blind trial.
Topics: Acute Disease; Adult; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Huma | 1988 |
A controlled study on the effect of pentoxifylline and an ergot alkaloid derivative on regional cerebral blood flow in patients with chronic cerebrovascular disease.
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clinical Trials as Topic; E | 1988 |
[Experience with Cosaldon retard in double blind studies].
Topics: Aged; Aging; Brain; Cerebrovascular Disorders; Clinical Trials as Topic; Geriatrics; Humans; Nicotin | 1969 |
Other Studies
19 other studies available for theobromine and Brain Vascular Disorders
Article | Year |
---|---|
A CONTROLLED TRIAL OF COSALDON IN ARTERIOSCLEROTIC DEMENTIA.
Topics: Arteriosclerosis; Biomedical Research; Cerebrovascular Disorders; Dementia; Dementia, Vascular; Drug | 1964 |
The effect of pentoxifylline on red cell deformability in cerebrovascular accidents.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Capillary Permeability; Cerebrovascular Disorders; Drug Th | 1980 |
Hemorheological effects of pentoxifylline on disturbed flow behavior of blood in patients with cerebrovascular insufficiency.
Topics: Adenosine Diphosphate; Blood Viscosity; Cerebrovascular Disorders; Epinephrine; Erythrocytes; Female | 1983 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
Special therapeutical aspects of cerebrovascular disease.
Topics: Aspirin; Cerebrovascular Disorders; Drug Combinations; Female; Humans; Male; Pentoxifylline; Platele | 1981 |
Hemorheologic conditions in patients with cerebrovascular disease altered by treatment with pentoxifylline.
Topics: Blood Viscosity; Cerebrovascular Disorders; Drug Evaluation; Female; Fibrinogen; Hematocrit; Humans; | 1981 |
Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease.
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Female; Humans; Male; | 1981 |
[Treatment of cardiac and cerebrovascular insufficiency with Card-Cosaldon. Result of a field study].
Topics: Aged; Cerebrovascular Disorders; Digoxin; Drug Combinations; Drug Evaluation; Female; Heart Diseases | 1979 |
Clinical evaluation of the effect of pentoxifylline on circulatory behavior of the brain.
Topics: Adult; Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Male; Middle Ag | 1979 |
[Combination of phosphatidylcholine and pentoxifylline in the therapy of progressive obstructive stroke].
Topics: Aged; Blood Viscosity; Cerebrovascular Disorders; Drug Therapy, Combination; Female; Humans; Male; P | 1979 |
Measurement of cerebral blood flow following intravenous administration of pentoxifyline ('Trentral').
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; Injections, Intravenou | 1977 |
[5 years of clinico-experimental and therapeutic experiences with pentoxifylline].
Topics: Arterial Occlusive Diseases; Cerebrovascular Disorders; Chemical Phenomena; Chemistry; Eye Diseases; | 1977 |
[Treatment of cerebrovascular insufficiency symptoms. Experience from practice].
Topics: Adult; Aged; Cerebrovascular Disorders; Drug Combinations; Female; Humans; Male; Middle Aged; Neurol | 1976 |
Pentoxifylline alters the natural course of acute nonhemorrhagic stroke.
Topics: Acute Disease; Cerebrovascular Disorders; Humans; Nervous System; Pentoxifylline; Theobromine | 1990 |
Pentoxifylline increases cerebral blood flow in patients with cerebrovascular disease.
Topics: Aged; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; Dose-Response Relation | 1989 |
Possible complications of pentoxifylline in stroke.
Topics: Animals; Cerebrovascular Disorders; Humans; Pentoxifylline; Receptors, Purinergic; Theobromine | 1989 |
Results of hemorheologically active treatment with pentoxifylline in patients with cerebrovascular disease.
Topics: Blood Pressure; Blood Viscosity; Cerebrovascular Disorders; Erythrocyte Aggregation; Erythrocyte Def | 1989 |
[Effect of the long-term prophylactic use of trental on cerebral blood flow in diabetics].
Topics: Adult; Cerebrovascular Disorders; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Diabet | 1988 |
[Indications for using trental in the initial manifestations of inadequate blood supply to the brain].
Topics: Adult; Blood Coagulation; Blood Viscosity; Cerebrovascular Circulation; Cerebrovascular Disorders; F | 1986 |