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theobromine and Blood Pressure, High

theobromine has been researched along with Blood Pressure, High in 23 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Research Excerpts

ExcerptRelevanceReference
" The bioavailability of this polyphenol-rich cocoa powder developed at pilot scale was previously demonstrated in humans."1.35Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans. ( Aleixandre, A; Cienfuegos-Jovellanos, E; Miguel, M; Moulay, L; Muguerza, B; Quiñones, Mdel M, 2009)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's0 (0.00)18.2507
2000's2 (8.70)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, SB1
Li, YF1
Mao, ZF1
Hu, HH1
Ouyang, SH1
Wu, YP1
Tsoi, B1
Gong, P1
Kurihara, H1
He, RR1
Guessous, I1
Pruijm, M1
Ponte, B1
Ackermann, D1
Ehret, G1
Ansermot, N1
Vuistiner, P1
Staessen, J1
Gu, Y1
Paccaud, F1
Mohaupt, M1
Vogt, B1
Pechère-Bertschi, A1
Pechère-Berstchi, A1
Martin, PY1
Burnier, M1
Eap, CB1
Bochud, M1
Cienfuegos-Jovellanos, E1
Quiñones, Mdel M1
Muguerza, B1
Moulay, L1
Miguel, M1
Aleixandre, A1
HACKENBERG, R1
HAUSLER, HP1
JOB, C1
ZELLNER, H1
COHEN, BM2
KORTGE, P1
KUHNE, P1
SCHULTZ, GW1
SCHENK, H1
FRANKE, G1
THIEME, HJ1
BECKMANN, G1
CARLIZZA, L1
FUJIHARA, M1
TAKAHASHI, I1
HAYASHI, K1
TANAKA, M1
Fahim, M1
Mustafa, SJ1
Dembowski, U1
Marx-Heep, I1
Adams, HJ1
Tikhonov, VP1
Statsenko, ME1
Trimarco, B1
Lembo, G1
De Luca, N1
Ricciardelli, B1
Rosiello, G1
Volpe, M1
Orofino, G1
Condorelli, M1
Quirk, WS1
Dengerink, HA1
Bademian, MJ1
Hall, KW1
Wright, JW1
Iunusov, RA1
Burykh, LN1
Sviridova, NI1
Shoĭkhet, IN1
Treĭvish, VS1
Novikova, NN1
Rafibekova, ZhS1
Radzvilovskaia, ME1
Bobusheva, GS1
Dzhumagulova, AS1
Solerte, SB1
Adamo, S1
Viola, C1
Zambianchi, E1
Ferrari, E1
Dammann, C1

Trials

3 trials available for theobromine and Blood Pressure, High

ArticleYear
Effects of celiprolol on systemic and forearm circulation in hypertensive patients: a double-blind cross-over study versus metoprolol.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Celiprolol; Double-Blind Method; Echocardiography; Female; Forea

1987
[Pentoxifylline and arterial hypertension in diabetes mellitus: long-term results in randomized groups].
    La Ricerca in clinica e in laboratorio, 1985, Volume: 15 Suppl 1

    Topics: Diabetes Complications; Erythrocyte Deformability; Follow-Up Studies; Humans; Hypertension; Pentoxif

1985
[Experiences with new Cosaldon forms].
    Medizinische Klinik, 1969, Feb-21, Volume: 64, Issue:8

    Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Dosage Forms; Female; Geriatrics; Humans; Hypertension;

1969

Other Studies

20 other studies available for theobromine and Blood Pressure, High

ArticleYear
Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.
    Journal of the science of food and agriculture, 2015, Volume: 95, Issue:6

    Topics: Animals; Blood Pressure; Caffeine; Camellia sinensis; Epinephrine; Hypertension; Male; Norepinephrin

2015
Associations of ambulatory blood pressure with urinary caffeine and caffeine metabolite excretions.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm

2015
Correction.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:2

    Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm

2016
Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans.
    Journal of agricultural and food chemistry, 2009, Jul-22, Volume: 57, Issue:14

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cacao; Flavonoids; Food Handling; Hypertension; Ma

2009
[New perspectives in therapy of hypertonic symptom complex].
    Medizinische Klinik, 1953, Jan-30, Volume: 48, Issue:5

    Topics: Barbiturates; Humans; Hypertension; Papaverine; Theobromine

1953
[Pharmacological and clinical studies of a water-soluble theobromine derivative. II].
    Wiener medizinische Wochenschrift (1946), 1954, Jul-10, Volume: 104, Issue:28

    Topics: Angina Pectoris; Arteriosclerosis; Biomedical Research; Hypertension; Theobromine; Vasoconstrictor A

1954
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
    Military medicine, 1957, Volume: 120, Issue:2

    Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant

1957
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
    Military medicine, 1957, Volume: 120, Issue:2

    Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant

1957
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
    Military medicine, 1957, Volume: 120, Issue:2

    Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant

1957
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
    Military medicine, 1957, Volume: 120, Issue:2

    Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant

1957
[Analysis of circulation in hypertensive patients after parenteral administration of hydrosoluble theobromine derivatives].
    Arztliche Wochenschrift, 1957, Jun-21, Volume: 12, Issue:25

    Topics: Biological Phenomena; Blood Circulation; Hypertension; Pharmaceutical Preparations; Physiological Ph

1957
[Therapy of hypertension].
    Medizinische Klinik, 1958, Oct-10, Volume: 53, Issue:41

    Topics: Antihypertensive Agents; Digitalis; Humans; Hypertension; Secologanin Tryptamine Alkaloids; Theobrom

1958
[Therapy of hypertension with a Rauwolfia combination preparation].
    Therapie der Gegenwart, 1958, Volume: 97, Issue:12

    Topics: Alkaloids; Antihypertensive Agents; Digitalis; Digitalis Glycosides; Humans; Hypertension; Rauwolfia

1958
[Treatment of hypertension in geriatrics].
    Die Medizinische, 1959, Apr-25, Volume: 4, Issue:17

    Topics: Aged; Geriatrics; Humans; Hypertension; Oleic Acid; Oleic Acids; Theobromine

1959
[Clinical experimentation with a hydrosoluble derivative of theobromine].
    Clinique (Paris, France), 1961, Volume: 21

    Topics: Asthma; Cardiovascular Diseases; Empirical Research; Hypertension; Research Design; Theobromine

1961
[Experiences with the use of Tonostan tablets].
    [Chiryo] [Therapy], 1961, Volume: 43

    Topics: Humans; Hypertension; Niacin; Nicotinic Acids; Tablets; Theobromine

1961
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endotheliu

2001
[Angioneuropathies, angiolopathies and other disorders of blood circulation. Treatment in ambulatory patients].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1979, Oct-10, Volume: 55, Issue:28

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Obes

1979
[Pharmacologic correction of the adverse effects of beta-adrenoblockaders on the kidneys in patients with hypertension].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:3

    Topics: Adult; Aged; Female; Humans; Hypertension; Ischemia; Kidney; Male; Middle Aged; Pentoxifylline; Prop

1989
The effects of pentoxifylline on cochlear blood flow in normotensive and spontaneously hypertensive rats.
    Hearing research, 1988, Volume: 36, Issue:2-3

    Topics: Animals; Blood Pressure; Cochlea; Dose-Response Relationship, Drug; Hypertension; Infusions, Intrave

1988
[Hemodynamic assessment of anti-angina preparations in treating patients with ischemic heart disease with hypertension].
    Vrachebnoe delo, 1987, Issue:8

    Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Hum

1987
[Pentoxifylline (Trental) in the treatment of chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Chronic Disease; Drug Evaluation; Female; Glomerulonephritis; Humans; Hypertensio

1986
[Experience with the use of trental in the treatment of essential hypertension].
    Kardiologiia, 1985, Volume: 25, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Coagulation; Female; Humans; Hypertension; Male; Middle Aged;

1985