theobromine has been researched along with Blood Clot in 13 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Shunt thrombosis was assumed when the flow in the shunt discontinued under visual and auscultatory control." | 6.66 | Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo. ( Borić, Z; Muśikić, P; Naumović, T; Radmilović, A; Stamenković, M, 1987) |
| "The hamster cheek pouch model of experimental thrombosis in which thrombi are induced in the microvasculature by iontophoretical administration of adenosine diphosphate (ADP) was used to test the antithrombotic potential of pentoxifylline (Trental)." | 3.67 | Reduced thrombus formation in vivo after administration of pentoxifylline (Trental). ( Giessinger, N; Michal, M; Schröer, R, 1989) |
| "The effect of the combined oral administration of pentoxifylline (pof) and low dose acetylsalicylic acid (ASA) was evaluated with the help of the laser-induced thrombosis in rat mesenteric arterioles." | 3.67 | Surprising effects of the sequential administration of pentoxifylline and low dose acetylsalicylic acid on thrombus formation. ( Seiffge, D; Weithmann, KU, 1987) |
| "Shunt thrombosis was assumed when the flow in the shunt discontinued under visual and auscultatory control." | 2.66 | Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo. ( Borić, Z; Muśikić, P; Naumović, T; Radmilović, A; Stamenković, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lucas, MA | 1 |
| Müller, R | 2 |
| Zatevakhin, II | 1 |
| Koshkin, VM | 2 |
| Shestakov, VA | 1 |
| Il'in, SG | 1 |
| Adil'khanov, SG | 2 |
| Antonova, NIu | 1 |
| Lehrach, F | 1 |
| Theis, H | 1 |
| Michal, M | 1 |
| Giessinger, N | 1 |
| Schröer, R | 1 |
| Neugodov, IuV | 1 |
| Sokolov, GF | 1 |
| Popov, VV | 1 |
| El'skaia, IE | 1 |
| Seiffge, D | 2 |
| Weithmann, KU | 2 |
| Radmilović, A | 1 |
| Borić, Z | 1 |
| Naumović, T | 1 |
| Stamenković, M | 1 |
| Muśikić, P | 1 |
| Weichert, W | 1 |
| Breddin, HK | 1 |
| Schröer, RH | 1 |
| Kovaleva, LG | 1 |
| Sedova, GT | 1 |
| Krasiukova, LI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pentoxifylline Dose Optimization in Preterm Neonatal Late Onset Sepsis[NCT04152980] | Phase 3 | 40 participants (Anticipated) | Interventional | 2020-01-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for theobromine and Blood Clot
| Article | Year |
|---|---|
Pentoxifylline -- a biomedical profile.
Topics: Arterial Occlusive Diseases; Blood Viscosity; Brain Ischemia; Cerebrovascular Circulation; Erythrocy | 1979 |
2 trials available for theobromine and Blood Clot
| Article | Year |
|---|---|
Prevention of post-operative thrombosis in peripheral arteriopathies. Pentoxifylline vs. conventional antiaggregants: a six-month randomized follow-up study.
Topics: Aged; Aspirin; Dipyridamole; Drug Tolerance; Female; Follow-Up Studies; Humans; Male; Middle Aged; P | 1984 |
Shunt thrombosis prevention in hemodialysis patients--a double-blind, randomized study: pentoxifylline vs placebo.
Topics: Adult; Aged; Aged, 80 and over; Arteriovenous Shunt, Surgical; Clinical Trials as Topic; Double-Blin | 1987 |
10 other studies available for theobromine and Blood Clot
| Article | Year |
|---|---|
[Effect of papaverine and trental on hemostasis and rheologic properties of blood in acute arterial obstruction].
Topics: Acute Disease; Blood Viscosity; Hemostasis; Humans; Papaverine; Pentoxifylline; Theobromine; Thrombo | 1979 |
[Peripheral macro-and microcirculatory changes in acute arterial obstruction with papaverine and trental administration].
Topics: Acute Disease; Arterial Occlusive Diseases; Blood Circulation; Drug Evaluation; Embolism; Hemodynami | 1979 |
[5 years of clinico-experimental and therapeutic experiences with pentoxifylline].
Topics: Arterial Occlusive Diseases; Cerebrovascular Disorders; Chemical Phenomena; Chemistry; Eye Diseases; | 1977 |
Reduced thrombus formation in vivo after administration of pentoxifylline (Trental).
Topics: Adenosine Diphosphate; Animals; Cheek; Cricetinae; Fibrinolytic Agents; Injections, Intraperitoneal; | 1989 |
[The onset of circulatory venous gangrene of the arm and its successful treatment by thrombolysis].
Topics: Adult; Arm; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gangrene; Heparin; Humans; Infus | 1989 |
Update on the pharmacology of pentoxifylline and its combination with low-dose acetylsalicylic acid (HWA 5112).
Topics: Animals; Aspirin; Blood Flow Velocity; Blood Viscosity; Dose-Response Relationship, Drug; Drug Thera | 1989 |
Surprising effects of the sequential administration of pentoxifylline and low dose acetylsalicylic acid on thrombus formation.
Topics: Administration, Oral; Animals; Aspirin; Drug Administration Schedule; Drug Synergism; Lasers; Male; | 1987 |
Antithrombotic effects of acetylsalicylic acid (ASA) and pentoxifylline in laser-induced thrombosis in rat mesenteric vessels.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; In Vitro Techniques; Laser Therapy; Male; Mesent | 1985 |
Antithrombotic potential of pentoxifylline. A hemorheologically active drug.
Topics: Animals; Aspirin; Blood Coagulation; Cricetinae; Epoprostenol; Fibrinolysis; Haplorhini; Hemostasis; | 1985 |
[Preventive correction of hemostasis in patients with polycythemia vera].
Topics: Aspirin; Humans; Niacin; Pentoxifylline; Polycythemia Vera; Theobromine; Thrombosis | 1986 |