theobromine has been researched along with Bilateral Wilms Tumor in 2 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Excerpt | Relevance | Reference |
---|---|---|
"Pentoxifylline (Trental), a phosphodiesterase inhibitor with platelet aggregation inhibitory effect, was shown to decrease spontaneous metastases in a Wilms' tumor model in Furth-Wistar rats and in neuroblastoma C1300 in A/J mice." | 3.66 | Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis. ( Ambrus, JL; Cohen, H; Gastpar, H; Gordon, S; Murphy, GP; Sciandra, J; Williams, P; Witul, M, 1979) |
" In the present experiment pentoxifylline appears to be a highly effective platelet aggregation inhibitor: a dose-response curve is apparent in monkey between 6 and 24 mg/kg i." | 1.26 | Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis. ( Ambrus, CM; Ambrus, JL; Gastpar, H, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ambrus, JL | 2 |
Ambrus, CM | 1 |
Gastpar, H | 2 |
Gordon, S | 1 |
Witul, M | 1 |
Cohen, H | 1 |
Sciandra, J | 1 |
Williams, P | 1 |
Murphy, GP | 1 |
2 other studies available for theobromine and Bilateral Wilms Tumor
Article | Year |
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Effect of phosphodiesterase inhibitors on platelet aggregation and tumor metastasis.
Topics: Adenocarcinoma; Adenosine Diphosphate; Animals; Carcinoma, Ehrlich Tumor; Female; Head and Neck Neop | 1981 |
Studies on platelet aggregation inhibitors in vivo. VIII. Effect of pentoxifylline on spontaneous tumor metastasis.
Topics: Adenocarcinoma; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasm M | 1979 |