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theobromine and Atrophy

theobromine has been researched along with Atrophy in 3 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Theobromine was administered orally to male Sprague-Dawley rats at dose levels of 250 and 500 mg/kg for 2 weeks starting at the age of 6 or 8 weeks, and for 4 weeks from the age of 6 weeks."1.31Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 22). Effects of 2- and 4-week administration of theobromine on the testis. ( Fujioka, M; Funabashi, H; Kohchi, M; Matsuoka, N; Tateishi, Y, 2000)
"Pentoxifylline (Trental) has multiple mechanisms of action, including stimulation of prostacyclin synthesis, decreased aggregation of platelets, increased deformability of red blood cells, increased mobility of neutrophils, and increased fibrinolysis."1.27Therapy of livedo vasculitis with pentoxifylline. ( Bard, JW; Ely, H, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Funabashi, H1
Fujioka, M1
Kohchi, M1
Tateishi, Y1
Matsuoka, N1
Ely, H1
Bard, JW1
Sauer, GC1

Other Studies

3 other studies available for theobromine and Atrophy

ArticleYear
Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 22). Effects of 2- and 4-week administration of theobromine on the testis.
    The Journal of toxicological sciences, 2000, Volume: 25 Spec No

    Topics: Administration, Oral; Animals; Atrophy; Body Weight; Dose-Response Relationship, Drug; Epididymis; M

2000
Therapy of livedo vasculitis with pentoxifylline.
    Cutis, 1988, Volume: 42, Issue:5

    Topics: Adult; Atrophy; Female; Humans; Leg Ulcer; Middle Aged; Pentoxifylline; Skin; Theobromine; Wound Hea

1988
Pentoxifylline (Trental) therapy for the vasculitis of atrophie blanche.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Adult; Aged; Atrophy; Female; Humans; Leg; Male; Middle Aged; Pentoxifylline; Skin; Skin Diseases; T

1986