Page last updated: 2024-11-05

theobromine and Asthma, Bronchial

theobromine has been researched along with Asthma, Bronchial in 10 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Research Excerpts

ExcerptRelevanceReference
"The bronchodilator effect of a 10 mg/kg dose of theobromine (3,7-dimethylxanthine) was compared with that of 5 mg/kg of theophylline (1,3-dimethylxanthine) in young patients with asthma."9.05The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma. ( Becker, AB; Gillespie, CA; Simons, FE; Simons, KJ, 1985)
" Multivariable logistic or linear regression was used for the analysis of urinary levels of caffeine or each of its three major metabolites (paraxanthine, theobromine, and theophylline) and current asthma, lung function, and FeNO."8.12Urinary caffeine and caffeine metabolites, asthma, and lung function in a nationwide study of U.S. adults. ( Celedón, JC; Forno, E; Han, YY, 2022)
"The bronchodilator effect of a 10 mg/kg dose of theobromine (3,7-dimethylxanthine) was compared with that of 5 mg/kg of theophylline (1,3-dimethylxanthine) in young patients with asthma."5.05The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma. ( Becker, AB; Gillespie, CA; Simons, FE; Simons, KJ, 1985)
" The benefits of methylxanthine-based therapies in the apnea of prematurity and their translational potential in pediatric affections of the respiratory tract are here presented."4.93The potential of methylxanthine-based therapies in pediatric respiratory tract diseases. ( Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A, 2016)
" Multivariable logistic or linear regression was used for the analysis of urinary levels of caffeine or each of its three major metabolites (paraxanthine, theobromine, and theophylline) and current asthma, lung function, and FeNO."4.12Urinary caffeine and caffeine metabolites, asthma, and lung function in a nationwide study of U.S. adults. ( Celedón, JC; Forno, E; Han, YY, 2022)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Han, YY1
Forno, E1
Celedón, JC1
Oñatibia-Astibia, A1
Martínez-Pinilla, E1
Franco, R1
PARENTI, B1
DE MICHELI, E1
CARLIZZA, L1
ALTHAUS, G1
BIRON, A1
Goecke, IA1
Alvarez, C1
Henríquez, J1
Salas, K1
Molina, ML1
Ferreira, A1
Gatica, H1
Valia, KH1
Hartman, CA1
Kucharczyk, N1
Sofia, RD1
Johnson, GF1
Dechtiaruk, WA1
Solomon, HM1
Simons, FE1
Becker, AB1
Simons, KJ1
Gillespie, CA1

Reviews

1 review available for theobromine and Asthma, Bronchial

ArticleYear
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases.
    Respiratory medicine, 2016, Volume: 112

    Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans;

2016

Trials

1 trial available for theobromine and Asthma, Bronchial

ArticleYear
The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:5

    Topics: Adolescent; Asthma; Child; Female; Forced Expiratory Volume; Humans; Kinetics; Male; Theobromine; Th

1985

Other Studies

8 other studies available for theobromine and Asthma, Bronchial

ArticleYear
Urinary caffeine and caffeine metabolites, asthma, and lung function in a nationwide study of U.S. adults.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2022, Volume: 59, Issue:11

    Topics: Adult; Asthma; Bronchodilator Agents; Caffeine; Coffee; Cross-Sectional Studies; Humans; Lung; Nutri

2022
[1-(beta-Hydroxypropyl)-theobromine, by oral route and by aerosol, in the treatment of chronic bronchitis and bronchial asthma].
    Gazzetta medica italiana, 1961, Volume: 120

    Topics: Administration, Oral; Aerosols; Asthma; Bronchitis; Bronchitis, Chronic; Humans; Theobromine

1961
[Clinical experimentation with a hydrosoluble derivative of theobromine].
    Clinique (Paris, France), 1961, Volume: 21

    Topics: Asthma; Cardiovascular Diseases; Empirical Research; Hypertension; Research Design; Theobromine

1961
[Clinical observations in the treatment of bronchial asthma].
    Munchener medizinische Wochenschrift (1950), 1962, Nov-02, Volume: 104

    Topics: Anti-Allergic Agents; Asthma; Benactyzine; Gluconates; Histamine H1 Antagonists; Humans; Phenobarbit

1962
[CURRENT THERAPEUTIC METHODS IN THE THOROUGH TREATMENT OF ASTHMA].
    Concours medical, 1963, Dec-21, Volume: 85

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Allergic Agents; Asthma; Bloo

1963
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
    Molecular immunology, 2007, Volume: 44, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Asthma; Autoimmune Diseases; Drug Synergism; Gene Expr

2007
Simultaneous determination of dyphylline and theophylline in human plasma by high-performance liquid chromatography.
    Journal of chromatography, 1980, Nov-14, Volume: 221, Issue:1

    Topics: Asthma; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Reference Values; Theobr

1980
Gas-chromatographic determination of theophylline in human serum and saliva.
    Clinical chemistry, 1975, Volume: 21, Issue:1

    Topics: Asthma; Child; Chromatography, Gas; Evaluation Studies as Topic; Humans; Methods; Microchemistry; Ph

1975