theobromine has been researched along with Arteriosclerosis in 31 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with chronic occlusive arteriosclerosis received single oral doses of 100, 200, 400, 800, and 1200 mg pentoxifylline in a single-blind, placebo-controlled study." | 5.06 | Dose-response effects of pentoxifylline on erythrocyte filterability: clinical and animal model studies. ( Ambrus, JL; Anain, JM; Anain, PM; Anain, SM; Brobst, JA; Cobert, BL; Mitchell, P; Savitsky, JP; Stadler, S, 1990) |
| "A study was carried out in 127 patients (94 males and 33 females) presenting with arteriosclerosis (88 patients) or diabetic vasculopathy (39 patients) in different stages of severity (Fontaine) to assess the effectiveness and tolerance of treatment with high doses of pentoxifylline." | 3.67 | Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses. ( Antignani, PL; Bartolo, M; Pacino, G; Saliceti, F; Todini, AR, 1987) |
| "Pentoxifylline was used in the treatment of 90 patients with atherosclerosis-induced chronic peripheral arterial occlusive disease and diabetic vascular disorders in the lower extremities (clinical Fontaine Stages III and IV) for whom surgical reconstructive treatment was not indicated and who had shown inadequate response to previous therapy." | 1.27 | Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease. ( Seige, K; Sternitzky, R, 1985) |
| "The pentoxifylline-induced increase in RCF was less marked in Group II; only the rigidity parameter was significantly decreased." | 1.26 | Effect of pentoxifylline on red cell flexibility in arterio-sclerotic patients and in patients with heart valve prosthesis. ( Harjola, PT; Johnsson, R; Siltanen, P, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (96.77) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BRAECKELER, A | 1 |
| GRUNEIS, P | 1 |
| HAUSLER, HP | 1 |
| JOB, C | 1 |
| ZELLNER, H | 1 |
| JANTSCH, H | 1 |
| BEJDL, W | 2 |
| CZECH, W | 2 |
| EHRENREICH, R | 1 |
| SCHINKO, H | 1 |
| RADMAYER, E | 1 |
| COOPER, AJ | 1 |
| GAIER, H | 1 |
| Perhoniemi, V | 1 |
| Salmenkivi, K | 1 |
| Sundberg, S | 1 |
| Johnsson, R | 2 |
| Gordin, A | 1 |
| Maughan, RJ | 1 |
| Broom, J | 1 |
| Smith, G | 1 |
| Leiper, JB | 1 |
| Ah-See, AK | 1 |
| Engeset, J | 1 |
| Evan-Wong, A | 1 |
| Davidson, RJ | 1 |
| Harjola, PT | 1 |
| Siltanen, P | 1 |
| Shtok, VN | 1 |
| Fedorova, NV | 1 |
| Gadanova, IV | 1 |
| Vogralik, VG | 1 |
| Vogralik, MV | 1 |
| Runov, GP | 1 |
| Runova, AA | 1 |
| Kostrov, AI | 1 |
| Starzycka, M | 1 |
| Krukar-Bastrowa, K | 1 |
| Ambrus, JL | 2 |
| Ambrus, CM | 1 |
| Gastpar, H | 1 |
| Zielinski, HW | 2 |
| Syed, IB | 1 |
| Anain, JM | 2 |
| Anain, SM | 1 |
| Anain, PM | 1 |
| Stadler, S | 1 |
| Mitchell, P | 1 |
| Brobst, JA | 1 |
| Cobert, BL | 1 |
| Savitsky, JP | 1 |
| Schwartz, RW | 1 |
| Logan, NM | 1 |
| Johnson, PJ | 1 |
| Strodel, WE | 1 |
| Fine, JG | 1 |
| Kazmers, A | 1 |
| Hyde, GL | 1 |
| Manrique, RV | 1 |
| Manrique, V | 1 |
| Jarcusková, D | 1 |
| Uhrík, J | 1 |
| Sidorenko, GI | 1 |
| Tsapaev, VG | 1 |
| Tsapaeva, NL | 1 |
| Atroshchenko, ES | 1 |
| Antignani, PL | 1 |
| Todini, AR | 1 |
| Saliceti, F | 1 |
| Pacino, G | 1 |
| Bartolo, M | 1 |
| Wesołowski, J | 1 |
| Hubl, S | 1 |
| Szubski, J | 1 |
| Weinzieher, E | 1 |
| Rykowski, H | 1 |
| Sternitzky, R | 1 |
| Seige, K | 1 |
| Woosley, RL | 1 |
| Will, DH | 1 |
| Stark, H | 1 |
| Dammann, C | 1 |
| Alberto, S | 1 |
| Brusasco, L | 1 |
| Colongo, PG | 1 |
1 review available for theobromine and Arteriosclerosis
| Article | Year |
|---|---|
The effects of caffeine.
Topics: Adult; Arteriosclerosis; Caffeine; Child, Preschool; Female; Humans; Hypersensitivity; Infant; Male; | 1976 |
5 trials available for theobromine and Arteriosclerosis
| Article | Year |
|---|---|
Effects of flunarizine and pentoxifylline on walking distance and blood rheology in claudication.
Topics: Aged; Arteriosclerosis; Blood Pressure; Blood Viscosity; Cinnarizine; Clinical Trials as Topic; Doub | 1984 |
Dose-response effects of pentoxifylline on erythrocyte filterability: clinical and animal model studies.
Topics: Animals; Arteriosclerosis; Disease Models, Animal; Dose-Response Relationship, Drug; Erythrocyte Def | 1990 |
[Clinical evaluation of the preparation Trental].
Topics: Adult; Aged; Arteriosclerosis; Clinical Trials as Topic; Female; Humans; Leg; Male; Middle Aged; Pen | 1985 |
[The treatment of retinal circulatory disorders in practice. A contribution to the cooperation between the internist and the ophthalmologist].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Circulation; Clinical Trials as Topic; Diabetic Ret | 1965 |
[Experiences with new Cosaldon forms].
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Dosage Forms; Female; Geriatrics; Humans; Hypertension; | 1969 |
25 other studies available for theobromine and Arteriosclerosis
| Article | Year |
|---|---|
[Therapeutic experiences with theomagnol].
Topics: Arteriosclerosis; Humans; Oleic Acid; Oleic Acids; Theobromine | 1952 |
[Clinical experiences with theobromine-magnesium-oleate (perscleran) in atherosclerosis. I].
Topics: Arteriosclerosis; Atherosclerosis; Humans; Magnesium; Oleic Acid; Theobromine | 1953 |
[Pharmacological and clinical studies of a water-soluble theobromine derivative. II].
Topics: Angina Pectoris; Arteriosclerosis; Biomedical Research; Hypertension; Theobromine; Vasoconstrictor A | 1954 |
[Therapy of peripheral arteriosclerosis; effects of theobromine-magnesium oleate on the oscillogram of the extremities].
Topics: Arteriosclerosis; Humans; Magnesium; Oleic Acid; Oscillometry; Peripheral Vascular Diseases; Theobro | 1956 |
[Experimental studies on atherosclerosis and its control by theobromine with magnesium oleate].
Topics: Arteriosclerosis; Atherosclerosis; Magnesium; Oleic Acid; Theobromine | 1956 |
[Experimental studies on atherosclerosis and its control by theobromine with magnesium oleate].
Topics: Arteriosclerosis; Atherosclerosis; Magnesium; Oleic Acid; Theobromine | 1956 |
[Experimental studies on atherosclerosis and its control by theobromine with magnesium oleate].
Topics: Arteriosclerosis; Atherosclerosis; Magnesium; Oleic Acid; Theobromine | 1956 |
[Experimental studies on atherosclerosis and its control by theobromine with magnesium oleate].
Topics: Arteriosclerosis; Atherosclerosis; Magnesium; Oleic Acid; Theobromine | 1956 |
[Clinical results with perskleran in ambulatory therapy of arteriosclerosis].
Topics: Arteriosclerosis; Oleic Acid; Oleic Acids; Theobromine | 1957 |
[Therapeutic experiences in treatment of cerebral sclerosis with theomagnol].
Topics: Arteriosclerosis; Oleic Acid; Oleic Acids; Theobromine; Tuberous Sclerosis | 1958 |
A CONTROLLED TRIAL OF COSALDON IN ARTERIOSCLEROTIC DEMENTIA.
Topics: Arteriosclerosis; Biomedical Research; Cerebrovascular Disorders; Dementia; Dementia, Vascular; Drug | 1964 |
[Experience with theobromine-magnesium oleate (ThMO) in peripheral sclerotic circulatory disorders].
Topics: Arteriosclerosis; Cardiovascular Diseases; Humans; Magnesium; Oleic Acid; Oleic Acids; Theobromine | 1955 |
Whole blood and red cell ATP content in patients with peripheral vascular disease: the effect of cigarette smoking and oxpentifylline.
Topics: Adenosine Triphosphate; Age Factors; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Erythrocyt | 1984 |
Effect of pentoxifylline on red cell flexibility in arterio-sclerotic patients and in patients with heart valve prosthesis.
Topics: Adult; Aortic Valve; Arteriosclerosis; Erythrocyte Membrane; Erythrocytes; Female; Heart Valve Prost | 1981 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
[Trental treatment of microcirculatory disorders in diabetes mellitus and arteriosclerosis].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Blood Viscosity; Diabetic Angiopathies; Drug Evaluation; | 1982 |
[Cosaldon retard in the treatment of certain maculopathies (author's transl)].
Topics: Adult; Aged; Arteriosclerosis; Drug Combinations; Female; Humans; Macular Degeneration; Male; Middle | 1980 |
Studies on platelet aggregation with pentoxifylline: effect on neoplastic disorders and other new indications.
Topics: Anemia, Sickle Cell; Animals; Arteriosclerosis; Blood Viscosity; Embolism; Haplorhini; Humans; Neopl | 1979 |
[On the treatment of arteriosclerotic retinopathy with Cosaldon A+E (author's transl)].
Topics: Adult; Aged; Arteriosclerosis; Chorioretinitis; Drug Combinations; Female; Humans; Male; Middle Aged | 1978 |
Pentoxifylline increases extremity blood flow in diabetic atherosclerotic patients.
Topics: Arteries; Arteriosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Exercise Test; Female; Humans; | 1989 |
Platelet resistance to prostacyclin. Enhancement of the antiaggregatory effect of prostacyclin by pentoxifylline.
Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Blood Platelets; Cyclic AMP; Drug Resist | 1987 |
[Evaluation of thermal conductivity and skin temperature in the treatment of leg ulcers].
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Diabetic Angiopathies; Female; Humans; Leg; Leg Ul | 1988 |
[Effect of treatment with trental on indicators of peripheral hemodynamics and blood lipid level in patients with arteriosclerosis of the lower extremities].
Topics: Arteriosclerosis; Capillary Permeability; Hemodynamics; Humans; Leg; Lipids; Male; Pentoxifylline; T | 1987 |
Results of clinical, laboratory and haemorheological investigations of the use of pentoxifylline in high doses.
Topics: Aged; Arteriosclerosis; Blood Pressure; Diabetic Angiopathies; Erythrocyte Deformability; Female; Hu | 1987 |
Clinical investigation of the effects of pentoxifylline in patients with severe peripheral occlusive vascular disease.
Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Diabetes Mellitus, Type 1; Diabetes Mell | 1985 |
Influence of theobromine magnesium oleate on formation of experimental atheroma.
Topics: Administration, Oral; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol; Diet, Atherogenic; | 1973 |
[Experience with Cosaldon in the treatment of circulatory disorders in the ophthalmological practice].
Topics: Arteriosclerosis; Diabetic Retinopathy; Glaucoma; Humans; Ophthalmoplegia; Optic Nerve; Retinal Dege | 1969 |
[On the use of an association of ATP, cocarboxylase and beta-hydroxy-propyl-theobromine in cardiovascular therapy].
Topics: Adenosine Triphosphate; Adult; Aged; Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Femal | 1966 |