theobromine has been researched along with Acute Kidney Failure in 2 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beneficial effects of post-insult administration of pentoxifylline, a novel hemorheologic agent experimentally studied in various ischemic diseases, were evaluated in two models of acute renal failure (ARF): direct nephrotoxicity (mercuric chloride 4 mg/kg via femoral vein) and hemoglobinuria (glycerol 10 ml/kg i." | 3.67 | Effects of pentoxifylline in experimental acute renal failure. ( Brunner, LJ; Luke, DR; Vadiei, K, 1989) |
| " A total of 48 rats were orally dosed with CSA 25 mg/kg for 10 days with either PTX 45 mg/kg i." | 1.28 | Prevention of cyclosporine-induced nephrotoxicity with pentoxifylline. ( Brunner, LJ; Iyer, LV; Luke, DR; Vadiei, K, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brunner, LJ | 2 |
| Vadiei, K | 2 |
| Iyer, LV | 1 |
| Luke, DR | 2 |
2 other studies available for theobromine and Acute Kidney Failure
| Article | Year |
|---|---|
Prevention of cyclosporine-induced nephrotoxicity with pentoxifylline.
Topics: Acute Kidney Injury; Animals; Biological Availability; Cyclosporins; Disease Models, Animal; Epopros | 1989 |
Effects of pentoxifylline in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Glycerol; Hemogl | 1989 |