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theobromine and Abnormalities, Drug-Induced

theobromine has been researched along with Abnormalities, Drug-Induced in 9 studies

Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patera, J1
Chorostowska-Wynimko, J1
Słodkowska, J1
Borowska, A1
Skopiński, P1
Sommer, E1
Wasiutyński, A1
Skopińska-Rózewska, E1
Nakatsuka, T1
Hanada, S1
Fujii, T2
Tanaka, H1
Nakazawa, K1
Arima, M1
Iwasaki, S1
Nomura, T1
Dawson, DA1
Bantle, JA1
Tarka, SM2
Applebaum, RS2
Borzelleca, JF2
York, RG1
Randall, JL1
Scott, WJ1
Nishimura, H1

Other Studies

9 other studies available for theobromine and Abnormalities, Drug-Induced

ArticleYear
Morphometric and functional abnormalities of kidneys in the progeny of mice fed chocolate during pregnancy and lactation.
    Folia histochemica et cytobiologica, 2006, Volume: 44, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Animals, Suckling; Cacao; Creatinine; Female

2006
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
    Teratology, 1983, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female;

1983
Caffeine and its dimethylxanthines and fetal cerebral development in rat.
    Brain & development, 1984, Volume: 6, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregn

1984
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; M

1983
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
    Teratology, 1987, Volume: 35, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, N

1987
Evaluation of the teratogenic potential of cocoa powder and theobromine in New Zealand White rabbits.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cacao; Dose-Response Relationship, Drug; Femal

1986
Evaluation of the perinatal, postnatal and teratogenic effects of cocoa powder and theobromine in Sprague-Dawley/CD rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Body Weight; Bone and Bones; Cacao; Dose-Res

1986
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
    Teratology, 1986, Volume: 34, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Fema

1986
Teratogenic actions of some methylated xanthines in mice.
    Okajimas folia anatomica Japonica, 1969, Volume: 46, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Injections, Intraperitoneal; Male; Mi

1969