theanine and Retinal-Neovascularization

theanine has been researched along with Retinal-Neovascularization* in 1 studies

Other Studies

1 other study(ies) available for theanine and Retinal-Neovascularization

Article	Year
[The effect of theanine on oxygen-induced retinal neovascularization in the neonatal rat]. Nippon Ganka Gakkai zasshi, 2008, Volume: 112, Issue:8 This study was aimed to investigate the preventive effects of theanine treatment on a rat model of oxygen-induced ischemic retinopathy (OIR).. OIR was induced by maintaining the Sprague-Dawley neonatal rats in 80% oxygen. The rats were treated once daily with gastric gavage of theanine (5 or 50 mg/kg) or distilled water (DW) from postnatal days 6 to 17. The retinal neovascularization (NV) was scored and avascular areas(AVAs) were measured as a % of total retinal area (% AVAs) at day 18.. The % AVAs in 5 mg/kg theanine (13.2 +/- 2.8%) and 50 mg/kg theanine (9.4 +/- 2.2%, p < 0.05) treatment were lower than those in DW (18.9 +/- 2.9 %). The NV scores with 5 mg/kg theanine(4.2 +/- 0.5) or 50 mg/kg theanine (3.4 +/- 0.6) treatment were lower than those with DW (4.7 +/- 0.6).. Theanine treatment suppresses the neovascularization in a rat model of OIR. These results suggest that theanine may prevent retinopathy of prematurity. Topics: Animals; Animals, Newborn; Glutamates; Oxygen; Rats; Rats, Sprague-Dawley; Retinal Neovascularization	2008

Article

Year

[The effect of theanine on oxygen-induced retinal neovascularization in the neonatal rat].

Nippon Ganka Gakkai zasshi, 2008, Volume: 112, Issue:8

This study was aimed to investigate the preventive effects of theanine treatment on a rat model of oxygen-induced ischemic retinopathy (OIR).. OIR was induced by maintaining the Sprague-Dawley neonatal rats in 80% oxygen. The rats were treated once daily with gastric gavage of theanine (5 or 50 mg/kg) or distilled water (DW) from postnatal days 6 to 17. The retinal neovascularization (NV) was scored and avascular areas(AVAs) were measured as a % of total retinal area (% AVAs) at day 18.. The % AVAs in 5 mg/kg theanine (13.2 +/- 2.8%) and 50 mg/kg theanine (9.4 +/- 2.2%, p < 0.05) treatment were lower than those in DW (18.9 +/- 2.9 %). The NV scores with 5 mg/kg theanine(4.2 +/- 0.5) or 50 mg/kg theanine (3.4 +/- 0.6) treatment were lower than those with DW (4.7 +/- 0.6).. Theanine treatment suppresses the neovascularization in a rat model of OIR. These results suggest that theanine may prevent retinopathy of prematurity.

Topics: Animals; Animals, Newborn; Glutamates; Oxygen; Rats; Rats, Sprague-Dawley; Retinal Neovascularization

2008