thapsigargin has been researched along with Laryngeal-Neoplasms* in 1 studies
1 other study(ies) available for thapsigargin and Laryngeal-Neoplasms
| Article | Year |
|---|---|
Effects of ascorbic acid on calcium signaling in tumor cells.
Effects of ascorbic acid on calcium homeostasis of human laryngeal carcinoma cells were studied. Intracellular concentration of free calcium and intracellular pH were measured by fluorescent analysis. Ascorbic acid in concentrations of 3-10 mM caused pH drop and sharply increased concentrations of free Ca ions in HEp-2 cells. Intracellular concentration of free Ca ions resulted from Ca ion release from the thapsigargin-sensitive Ca depots. Topics: Antioxidants; Ascorbic Acid; Calcium; Calcium Signaling; Carcinoma; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Fluorescence; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intracellular Space; Laryngeal Neoplasms; Oxidants; Thapsigargin; Time Factors | 2009 |