thallium-201 and Kidney-Failure--Chronic

This study aimed to investigate whether indices of left ventricular (LV) dyssynchrony by gated myocardial perfusion SPECT (GMPS) could be useful to predict prognosis in chronic kidney disease (CKD) patients with normal perfusion defect scores.. One hundred and sixty-seven CKD patients with normal perfusion defect scores on adenosine-stress. The MACEs occurred in 12 patients (7.1%). Patients who experienced MACEs showed significantly higher PSD and wider BW than those who did not. In the Kaplan-Meier event-free survival analysis, cardiac event rate was significantly higher in the high-PSD and wide-BW group (n = 81) than in the low-PSD and narrow-BW group (n = 71) (P = .002). The multivariate regression analysis revealed that the PSD was associated with MACEs (odds ratio 1.33, 95% confidence interval 1.05-1.69, P = .01).. The LV dyssynchrony indices from GMPS may be novel prognostic predictors in CKD patients with normal perfusion defect scores.

Topics: Aged; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Female; Heart Ventricles; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Perfusion Imaging; Prognosis; Retrospective Studies; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Ventricular Dysfunction, Left