thalidomide has been researched along with Wasting Disease in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thalidomide, at the dosage used in this study, had no effect on peripheral CD4+ T cells nor on HIV viral burden in PBMC." | 2.68 | Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double-blind, placebo-controlled clinical trial. ( Arroyo-Figueroa, H; Calva, JJ; Martínez del Cerro, V; Pasquetti, A; Reyes-Terán, G; Ruiz-Palacios, GM; Sierra-Madero, JG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reyes-Terán, G | 1 |
| Sierra-Madero, JG | 1 |
| Martínez del Cerro, V | 1 |
| Arroyo-Figueroa, H | 1 |
| Pasquetti, A | 1 |
| Calva, JJ | 1 |
| Ruiz-Palacios, GM | 1 |
| Haslett, PA | 1 |
1 review available for thalidomide and Wasting Disease
| Article | Year |
|---|---|
Anticytokine approaches to the treatment of anorexia and cachexia.
Topics: Anorexia; Cachexia; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Pentoxifylline; | 1998 |
1 trial available for thalidomide and Wasting Disease
| Article | Year |
|---|---|
Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Adult; CD4 Lymphocyte Count; Cells, Cultured; Double-Blind Method; Female; Follow-Up Studies; HIV In | 1996 |
1 other study available for thalidomide and Wasting Disease
| Article | Year |
|---|---|
Thalidomide slows wasting in some pancreatic cancers.
Topics: Body Weight; Humans; Pancreatic Neoplasms; Thalidomide; Wasting Syndrome | 2005 |