thalidomide has been researched along with Wallerian Degeneration in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Wallerian Degeneration: Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Wallerian degeneration is a potent experimental model for studying reproducible cell proliferation in vivo." | 5.29 | Inhibitory effects of thalidomide on cellular proliferation, endoneurial edema and myelin phagocytosis during early wallerian degeneration. ( Kögel, B; Schröder, JM; Sellhaus, B; Wöhrmann, T; Zwingenberger, K, 1995) |
| "Wallerian degeneration is a potent experimental model for studying reproducible cell proliferation in vivo." | 1.29 | Inhibitory effects of thalidomide on cellular proliferation, endoneurial edema and myelin phagocytosis during early wallerian degeneration. ( Kögel, B; Schröder, JM; Sellhaus, B; Wöhrmann, T; Zwingenberger, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schröder, JM | 1 |
| Sellhaus, B | 1 |
| Wöhrmann, T | 1 |
| Kögel, B | 1 |
| Zwingenberger, K | 1 |
1 other study available for thalidomide and Wallerian Degeneration
| Article | Year |
|---|---|
Inhibitory effects of thalidomide on cellular proliferation, endoneurial edema and myelin phagocytosis during early wallerian degeneration.
Topics: Animals; Brain Edema; Cell Division; Myelin Sheath; Phagocytosis; Rats; Rats, Wistar; Schwann Cells; | 1995 |