Page last updated: 2024-11-05

thalidomide and Ulcer

thalidomide has been researched along with Ulcer in 38 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)."9.22Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022)
"A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV)."9.09Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. ( Basgoz, N; Chernoff, M; Fahey, JL; Fox, L; Hooton, TM; Jackson, JB; Jacobson, JM; MacPhail, LA; Sha, BE; Shikuma, CM; Simpson, DM; Spritzler, J; Trapnell, CB; Wohl, DA; Wu, AW, 1999)
"Though thalidomide in a dosage of 100 mg/day is the standard treatment for recurrent oral and genital ulcers (OGU), its toxicity would be less important with lower dosage, while its efficacy would be identical."9.09[Treatment of recurrent ulceration with low doses of thalidomide. Pilot study in 17 patients]. ( Berthier, S; de Wazières, B; Dupond, JL; Gil, H; Magy, N; Vuitton, DA, 1999)
"Thalidomide appears to be highly effective for oropharyngeal apthous ulcers in HIV-infected patients."9.08A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers. ( Alexander, LN; Wilcox, CM, 1997)
"Thalidomide is effective for treating the oral and genital ulcers and follicular lesions of the Behçet syndrome."9.08Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo-controlled trial. ( Hamuryudan, V; Mat, C; Ozyazgan, Y; Saip, S; Siva, A; Yazici, H; Yurdakul, S; Zwingenberger, K, 1998)
"An interim analysis of data from a NIAID-supported study determined that thalidomide effectively and safely heals severe mouth ulcers in persons with HIV infection."9.08Thalidomide effective treatment for AIDS-related mouth ulcers. ( Randall, P, 1995)
"Thalidomide was given to 15 patients with severe orogenital ulceration (OGU)."9.05Thalidomide in severe orogenital ulceration. ( Allen, BR; Jenkins, JS; Littlewood, SM; Maurice, PD; Powell, RJ; Smith, NJ, 1984)
"To examine the efficacy, dose, and safety profile, including neurophysiological testing of thalidomide used in 59 patients (including 23 with Behçet's disease) to treat severe oral or genital ulceration (OGU)."7.69Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy. ( Gardner-Medwin, JM; Powell, RJ; Smith, NJ, 1994)
"This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)."5.22Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022)
"A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV)."5.09Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. ( Basgoz, N; Chernoff, M; Fahey, JL; Fox, L; Hooton, TM; Jackson, JB; Jacobson, JM; MacPhail, LA; Sha, BE; Shikuma, CM; Simpson, DM; Spritzler, J; Trapnell, CB; Wohl, DA; Wu, AW, 1999)
"Though thalidomide in a dosage of 100 mg/day is the standard treatment for recurrent oral and genital ulcers (OGU), its toxicity would be less important with lower dosage, while its efficacy would be identical."5.09[Treatment of recurrent ulceration with low doses of thalidomide. Pilot study in 17 patients]. ( Berthier, S; de Wazières, B; Dupond, JL; Gil, H; Magy, N; Vuitton, DA, 1999)
"Thalidomide appears to be highly effective for oropharyngeal apthous ulcers in HIV-infected patients."5.08A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers. ( Alexander, LN; Wilcox, CM, 1997)
"Thalidomide is effective for treating the oral and genital ulcers and follicular lesions of the Behçet syndrome."5.08Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo-controlled trial. ( Hamuryudan, V; Mat, C; Ozyazgan, Y; Saip, S; Siva, A; Yazici, H; Yurdakul, S; Zwingenberger, K, 1998)
"An interim analysis of data from a NIAID-supported study determined that thalidomide effectively and safely heals severe mouth ulcers in persons with HIV infection."5.08Thalidomide effective treatment for AIDS-related mouth ulcers. ( Randall, P, 1995)
"Thalidomide was given to 15 patients with severe orogenital ulceration (OGU)."5.05Thalidomide in severe orogenital ulceration. ( Allen, BR; Jenkins, JS; Littlewood, SM; Maurice, PD; Powell, RJ; Smith, NJ, 1984)
"To examine the efficacy, dose, and safety profile, including neurophysiological testing of thalidomide used in 59 patients (including 23 with Behçet's disease) to treat severe oral or genital ulceration (OGU)."3.69Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy. ( Gardner-Medwin, JM; Powell, RJ; Smith, NJ, 1994)
"In a series of 12 patients suffering from an HIV infection, including 9 with confirmed AIDS, who complained about pharyngeal pain in a fixed site, having a progressive intensity and not relieved by antalgics and the specific treatments that were prescribed empirically, and for whom etiological investigation yielded negative results, Thalidomide proved to be the only effective means of healing the exulcerated, nail-mark lesions or the ulcerated, budding, neoplastic-like lesions, and of completely suppressing pain."3.68[Mouth and pharyngeal hyperalgesic syndromes in AIDS]. ( Barry, B; Depondt, J; Gehanno, P; Gorin, I; Guedon, C; Leport, C; Poignonec, S, 1990)
"Thalidomide was first used in the late 1950s but it was withdrawn from the market in the 1960s for its notorious teratogenic effects."2.42The promise of thalidomide: evolving indications. ( Joglekar, S; Levin, M, 2004)
"Thalidomide was withdrawn from world markets in 1961 following recognition of its teratogenic effects."1.33Thalidomide neuropathy in childhood. ( Chaitow, J; Darras, BT; Fleming, FJ; Jones, HR; Ryan, MM; Vytopil, M, 2005)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's24 (63.16)18.2507
2000's7 (18.42)29.6817
2010's1 (2.63)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Iizuka, Y1
Takase-Minegishi, K1
Hirahara, L1
Kirino, Y1
Soejima, Y1
Namkoong, HO1
Horita, N1
Yoshimi, R1
Takeuchi, M1
Takeno, M1
Mizuki, N1
Nakajima, H1
Hinojosa-Azaola, A1
Ramírez-Mulhern, I1
Figueroa-Pariente, A1
Martín-Nares, E1
Dauby, N1
Coussement, J1
Karakike, E1
Ungureanu, C1
De Wit, S1
Payen, MC1
Kolivras, A1
De Maubeuge, J1
André, J1
Song, M1
Joglekar, S1
Levin, M1
Fleming, FJ1
Vytopil, M1
Chaitow, J1
Jones, HR1
Darras, BT1
Ryan, MM1
Atiq, M1
Neff, GW1
Argyropoulos, C1
Schroer, M1
Kemmer, N1
Weber, F1
Buell, J1
Strauss, RM1
Bäte, J1
Nischal, KK1
Clayton, T1
Gooi, J1
Darling, JC1
Newton-Bishop, JA1
Verrou, E1
Kartsios, C1
Banti, A1
Mihou, D1
Kaloutsi, V1
Lazaridou, A1
Zervas, K1
Jenkins, JS1
Powell, RJ4
Allen, BR2
Littlewood, SM1
Maurice, PD2
Smith, NJ3
Bowers, PW1
Thompson, C1
Sire, S1
Fraisse, P1
Rey, D1
Jacquemin, C1
Kempf, G1
Partisani, M1
Lang, JM1
Naum, SM1
Molloy, PJ1
Kania, RJ1
McGarr, J1
Van Thiel, DH1
Gardner-Medwin, JM1
D'Arcy, PF1
Griffin, JP1
Verberkmoes, A1
Boer, K1
Wertheim, PM1
Bronkhorst, CM1
Lange, JM1
Couderc, LJ1
Balloul, E1
Caubarrere, I1
Domingo, P1
Ris, J1
López-Contreras, J1
DeVincenzo, JP1
Burchet, SK1
Louvel, D1
Musso, S1
Métivier, S1
Croizet, O1
Rouquet, RM1
Massip, P1
Escourrou, J1
Frexinos, J1
Bellomo, A1
Schorr-Lesnick, B1
Alexander, LN1
Wilcox, CM1
Hamuryudan, V1
Mat, C1
Saip, S1
Ozyazgan, Y1
Siva, A1
Yurdakul, S1
Zwingenberger, K1
Yazici, H1
Jibaly, RM1
Moallem, H1
Fikrig, SM1
Rabinowitz, SS1
Jacobson, JM1
Spritzler, J1
Fox, L1
Fahey, JL1
Jackson, JB1
Chernoff, M1
Wohl, DA1
Wu, AW1
Hooton, TM1
Sha, BE1
Shikuma, CM1
MacPhail, LA1
Simpson, DM1
Trapnell, CB1
Basgoz, N1
de Wazières, B1
Gil, H1
Magy, N1
Berthier, S1
Vuitton, DA1
Dupond, JL1
Ollivier, S1
Bonnet, J1
Lemann, M1
Coffin, JC1
Modigliani, R1
Jian, R1
Bertheau, P1
Flejou, JF1
Ryan, J2
Randall, P1
Colman, J1
Pedersen, J1
Gorin, I2
Vilette, B1
Gehanno, P2
Escande, JP1
Georghiou, PR1
Kemp, RJ1
Barry, B1
Depondt, J1
Guedon, C1
Poignonec, S1
Leport, C1
Bernardo, P1
Arrizabalaga, J1
Iribarren, JA1
Garde, C1
Lehner, T1
Sullivan, FM1
Jenkins, S1
Littlewood, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of a TNF-Alpha Modulator for the Treatment of Oral Lesions in HIV/AIDS Patients[NCT00001524]Phase 2110 participants Interventional1996-06-30Completed
A Pilot Trial of Topical Thalidomide for the Management of Chronic Discoid Lupus Erythematosus[NCT00001680]Phase 217 participants Interventional1997-10-31Completed
Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection[NCT00000790]Phase 2164 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for thalidomide and Ulcer

ArticleYear
Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis.
    Modern rheumatology, 2022, Oct-15, Volume: 32, Issue:6

    Topics: Arthritis; Behcet Syndrome; Genitalia; Humans; Oral Ulcer; Skin Ulcer; Thalidomide; Ulcer

2022
The promise of thalidomide: evolving indications.
    Drugs of today (Barcelona, Spain : 1998), 2004, Volume: 40, Issue:3

    Topics: Cachexia; Carcinoma, Renal Cell; Clinical Trials as Topic; Erythema Nodosum; Graft vs Host Disease;

2004
Thalidomide revisited.
    Adverse drug reactions and toxicological reviews, 1994,Summer, Volume: 13, Issue:2

    Topics: Abnormalities, Drug-Induced; Acquired Immunodeficiency Syndrome; Animals; Behcet Syndrome; Bone Marr

1994

Trials

8 trials available for thalidomide and Ulcer

ArticleYear
Thalidomide in severe orogenital ulceration.
    Lancet (London, England), 1984, Dec-22, Volume: 2, Issue:8417-8418

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Genital Diseases, Fe

1984
Thalidomide effective for AIDS-related oral ulcers.
    Lancet (London, England), 1995, Nov-11, Volume: 346, Issue:8985

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Esophageal Diseases; Humans; Placebos; Sto

1995
A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers.
    AIDS research and human retroviruses, 1997, Mar-01, Volume: 13, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Esophageal Diseases; Follow-Up Studies; HIV Infections; Humans; Prospectiv

1997
Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo-controlled trial.
    Annals of internal medicine, 1998, Mar-15, Volume: 128, Issue:6

    Topics: Adolescent; Adult; Behcet Syndrome; Double-Blind Method; Drug Administration Schedule; Follow-Up Stu

1998
Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antigens, CD; Double-Blind Method; Esophageal Diseases; E

1999
[Treatment of recurrent ulceration with low doses of thalidomide. Pilot study in 17 patients].
    La Revue de medecine interne, 1999, Volume: 20, Issue:7

    Topics: Adult; Behcet Syndrome; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Genital Disea

1999
Thalidomide effective in treating AIDS-related mouth ulcers.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Esophageal Diseases; Female; Humans; Immunosuppressive

1996
Thalidomide effective treatment for AIDS-related mouth ulcers.
    NIAID AIDS agenda, 1995

    Topics: Esophagus; HIV Infections; Humans; Placebos; Stomatitis, Aphthous; Thalidomide; Ulcer

1995

Other Studies

27 other studies available for thalidomide and Ulcer

ArticleYear
Clinical Characteristics and Outcomes of Mexican Patients With Behçet's Syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2023, Sep-01, Volume: 29, Issue:6

    Topics: Behcet Syndrome; Female; Humans; Immunosuppressive Agents; Male; Mexico; Thalidomide; Ulcer

2023
Acute myocardial infarction following thalidomide treatment for AIDS-related ulcers.
    AIDS (London, England), 2015, Jun-01, Volume: 29, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Coronary Angiography; Humans; Immune Reconstitution Infla

2015
Thalidomide in refractory vulvar ulcerations associated with Crohn's disease.
    Dermatology (Basel, Switzerland), 2003, Volume: 206, Issue:4

    Topics: Adult; Crohn Disease; Female; Humans; Immunosuppressive Agents; Thalidomide; Treatment Outcome; Ulce

2003
Thalidomide neuropathy in childhood.
    Neuromuscular disorders : NMD, 2005, Volume: 15, Issue:2

    Topics: Action Potentials; Adolescent; Brain Neoplasms; Child; Crohn Disease; Disease Progression; Electromy

2005
Successful treatment with thalidomide in a liver transplant recipient with giant esophageal ulcers.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2006, Volume: 12, Issue:6

    Topics: Aged; Esophageal Diseases; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Thalidomid

2006
A child with laryngo-onychocutaneous syndrome partially responsive to treatment with thalidomide.
    The British journal of dermatology, 2006, Volume: 155, Issue:6

    Topics: Adolescent; Conjunctival Diseases; Epidermolysis Bullosa; Female; Humans; Immunosuppressive Agents;

2006
IgG multiple myeloma presented with ulcerative pyoderma gangrenosum.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:7

    Topics: Dexamethasone; Humans; Male; Middle Aged; Multiple Myeloma; Pyoderma Gangrenosum; Thalidomide; Ulcer

2007
Effect of thalidomide on orogenital ulceration.
    British medical journal (Clinical research ed.), 1983, Sep-17, Volume: 287, Issue:6395

    Topics: Adult; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Recurrence; Stomatiti

1983
[Efficacy of thalidomide in the treatment of esophageal ulcers in human immunodeficiency virus infection].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Fatal Outcome; HIV Infections; HIV S

1995
Use of thalidomide in treatment and maintenance of idiopathic esophageal ulcers in HIV+ individuals.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Female; HIV Seropositivity; HIV-1; H

1995
Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Behcet Syndrome; Chronic Disease; Female; Genital Diseases, Female; Genital Disea

1994
Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Behcet Syndrome; Chronic Disease; Female; Genital Diseases, Female; Genital Disea

1994
Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Behcet Syndrome; Chronic Disease; Female; Genital Diseases, Female; Genital Disea

1994
Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Behcet Syndrome; Chronic Disease; Female; Genital Diseases, Female; Genital Disea

1994
Thalidomide for genital ulcer in HIV-positive woman.
    Lancet (London, England), 1996, Apr-06, Volume: 347, Issue:9006

    Topics: Adult; Female; Herpes Genitalis; HIV Seropositivity; HIV-1; Humans; Thalidomide; Ulcer; Vulvar Disea

1996
Esophageal ulcers in AIDS.
    Annals of internal medicine, 1996, May-15, Volume: 124, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Anti-Ulcer Agents; Esophageal Diseases; Humans; Thalidomide; Ulc

1996
Esophageal ulcers in AIDS.
    Annals of internal medicine, 1996, May-15, Volume: 124, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Anti-Ulcer Agents; Esophageal Diseases; Humans; Thalidomide; Ulc

1996
Prolonged thalidomide therapy for human immunodeficiency virus-associated recurrent severe esophageal and oral aphthous ulcers.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:5

    Topics: AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Child, Preschool; Esophageal Diseases;

1996
Idiopathic esophageal ulceration associated with human immunodeficiency virus infection: efficacy of thalidomide treatment.
    Endoscopy, 1996, Volume: 28, Issue:5

    Topics: Adult; Anti-Ulcer Agents; Esophageal Diseases; HIV Infections; Humans; Male; Thalidomide; Ulcer

1996
Thalidomide treatment for idiopathic esophageal ulcers in patients with HIV.
    Gastrointestinal endoscopy, 1996, Volume: 44, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Endoscopy, Digestive System; Esophageal Diseases; Humans;

1996
Steroid-resistant idiopathic esophageal ulcer in a child with AIDS.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 27, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Child, Preschool; Drug Resistance; Esophageal Disea

1998
Idiopathic giant oesophageal ulcer in an immunocompetent patient. The efficacy of thalidomide treatment.
    Gut, 1999, Volume: 45, Issue:3

    Topics: Esophageal Diseases; Humans; Immunocompetence; Immunosuppressive Agents; Male; Middle Aged; Thalidom

1999
Thalidomide treatment of oesophageal ulceration.
    Gut, 2000, Volume: 47, Issue:1

    Topics: Esophageal Diseases; Humans; Immunosuppressive Agents; Thalidomide; Ulcer

2000
Thalidomide to treat esophageal ulcer in AIDS.
    The New England journal of medicine, 1992, Jul-16, Volume: 327, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Humans; Male; Thalidomide; Ulcer

1992
Thalidomide in hyperalgic pharyngeal ulceration of AIDS.
    Lancet (London, England), 1990, Jun-02, Volume: 335, Issue:8701

    Topics: Acquired Immunodeficiency Syndrome; HIV Seropositivity; Homosexuality; Humans; Male; Middle Aged; Ph

1990
HIV-associated oesophageal ulcers treated with thalidomide.
    The Medical journal of Australia, 1990, Apr-02, Volume: 152, Issue:7

    Topics: Esophageal Diseases; HIV Infections; Humans; Male; Middle Aged; Thalidomide; Ulcer

1990
[Mouth and pharyngeal hyperalgesic syndromes in AIDS].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1990, Volume: 107, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Male; Middle Aged; Mouth Diseases; Pain;

1990
[Effectiveness of thalidomide in non specific esophageal ulcer in patients with acquired immunodeficiency syndrome].
    Medicina clinica, 1990, Apr-28, Volume: 94, Issue:16

    Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Humans; Male; Thalidomide; Ulcer

1990
Thalidomide, orogenital ulcers, and the risk of teratogenesis.
    Lancet (London, England), 1985, Feb-02, Volume: 1, Issue:8423

    Topics: Abnormalities, Drug-Induced; Female; Genital Diseases, Female; Humans; Mouth Diseases; Risk; Thalido

1985
Thalidomide, orogenital ulcers, and risk of teratogenicity.
    Lancet (London, England), 1985, Mar-02, Volume: 1, Issue:8427

    Topics: Abnormalities, Drug-Induced; Female; Genital Diseases, Female; Humans; Pregnancy; Risk; Stomatitis,

1985