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thalidomide and Toxoplasmosis, Congenital

thalidomide has been researched along with Toxoplasmosis, Congenital in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Toxoplasmosis, Congenital: Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morgon, A1
Charachon, D1
Bringuier, N1
Plum, P1

Other Studies

2 other studies available for thalidomide and Toxoplasmosis, Congenital

ArticleYear
Disorders of the auditory apparatus caused by embryopathy or foetopathy: prophylaxis and treatment (a) deafness as a result of congenital malformations occurring during the first three months (b) deafness resulting from diseases of the foetus occurring af
    Acta oto-laryngologica. Supplementum, 1971, Volume: 291

    Topics: Child, Preschool; Deafness; Ear; Ear, Inner; Female; Humans; Pregnancy; Pregnancy Complications; Rad

1971
[Human genetic perspectives. Antenatal and perinatal exogenous disease causes].
    Nordisk medicin, 1966, Jul-21, Volume: 76, Issue:29

    Topics: Abnormalities, Drug-Induced; Asphyxia Neonatorum; Brain Diseases; Genetics, Medical; Humans; Infant,

1966