Page last updated: 2024-11-05

thalidomide and Thyroid Diseases

thalidomide has been researched along with Thyroid Diseases in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Thyroid Diseases: Pathological processes involving the THYROID GLAND.

Research Excerpts

ExcerptRelevanceReference
" Central hypothyroidism is a well-recognized side effect of bexarotene."4.89Thyroid dysfunction as an unintended side effect of anticancer drugs. ( Appetecchia, M; Baldelli, R; Barnabei, A; Corsello, SM; Paragliola, R; Torino, F, 2013)
"Lenalidomide is an antiangiogenic drug associated with hypothyroidism."1.37Thyroid abnormalities in patients treated with lenalidomide for hematological malignancies: results of a retrospective case review. ( Brown, K; Clayton, W; Figaro, MK; Jagasia, S; Kassim, A; Lakhani, VT; Usoh, C, 2011)
"Goiter is relatively common in infants whose mothers were treated with propylthiouracil and other antithyroid drugs, yet they usually show normal thyroid function."1.25Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs. ( Shirkey, HC, 1972)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torino, F1
Barnabei, A1
Paragliola, R1
Baldelli, R1
Appetecchia, M1
Corsello, SM1
Figaro, MK1
Clayton, W1
Usoh, C1
Brown, K1
Kassim, A1
Lakhani, VT1
Jagasia, S1
Shirkey, HC1

Reviews

1 review available for thalidomide and Thyroid Diseases

ArticleYear
Thyroid dysfunction as an unintended side effect of anticancer drugs.
    Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:11

    Topics: Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agen

2013

Other Studies

2 other studies available for thalidomide and Thyroid Diseases

ArticleYear
Thyroid abnormalities in patients treated with lenalidomide for hematological malignancies: results of a retrospective case review.
    American journal of hematology, 2011, Volume: 86, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Female; Hematologic Neoplasms; Humans; Incidence; Le

2011
Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs.
    Advances in experimental medicine and biology, 1972, Volume: 27

    Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Antithyroid Agents; Contraceptives, Oral; Diethy

1972