thalidomide has been researched along with Syndrome in 66 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lenalidomide is an immunomodulatory agent approved for use in patients with myelodysplastic syndrome, and in combination with dexamethasone for refractory or relapsed multiple myeloma." | 7.74 | Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide. ( Abonour, R; Knox, K; Smith, P; Thornburg, A; Twigg, HL, 2007) |
| "Patients with relapsed chronic lymphocytic leukemia were treated with lenalidomide 20 mg (n=10) or 10 mg (n=8) daily for 3 weeks on a 6-week cycle." | 6.74 | Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia. ( Aue, G; Boss, C; Gibellini, F; Hughes, T; Keyvanfar, K; McCoy, JP; Njuguna, N; Pittaluga, S; Samsel, L; Soto, S; Tian, X; Valdez, J; Vire, B; Wiestner, A; Wilson, WH, 2009) |
| "Portal hypertension was induced by partial ligation of the portal vein (PVL)." | 5.29 | Thalidomide inhibits tumor necrosis factor alpha, decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal-hypertensive rats. ( Cadelina, G; Groszmann, RJ; Lopez-Talavera, JC; Merrill, W; Olchowski, J, 1996) |
| "Lenalidomide is an immunomodulatory agent approved for use in patients with myelodysplastic syndrome, and in combination with dexamethasone for refractory or relapsed multiple myeloma." | 3.74 | Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide. ( Abonour, R; Knox, K; Smith, P; Thornburg, A; Twigg, HL, 2007) |
| " Although treatment was initiated with thalidomide, the patient developed multiple organ dysfunction syndrome (MODS) and succumbed to his disease." | 3.73 | Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon. ( Bölke, E; Budach, W; Gripp, S; Orth, K; Peiper, M; Reinecke, P; Schwarz, A; van de Nes, JA, 2006) |
| "Patients with relapsed chronic lymphocytic leukemia were treated with lenalidomide 20 mg (n=10) or 10 mg (n=8) daily for 3 weeks on a 6-week cycle." | 2.74 | Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia. ( Aue, G; Boss, C; Gibellini, F; Hughes, T; Keyvanfar, K; McCoy, JP; Njuguna, N; Pittaluga, S; Samsel, L; Soto, S; Tian, X; Valdez, J; Vire, B; Wiestner, A; Wilson, WH, 2009) |
| "Proteus syndrome is an overgrowth syndrome caused by a somatic activating mutation in AKT1." | 2.61 | Vascular malformations syndromes: an update. ( Arias-Santiago, S; Martinez-Lopez, A; Molina-Leyva, A; Montero-Vilchez, T; Salvador-Rodriguez, L; Tercedor-Sanchez, J, 2019) |
| "Present knowledge of chromosomal aberrations associated with microphthalmia is surveyed, and some of the syndromes and phenocopies in the mentally retarded in which microphthalmia may be found are reviewed." | 2.35 | The heterogeneity of microphthalmia in the mentally retarded. ( Warburg, M, 1971) |
| "Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal." | 1.35 | Kaposiform hemangioendothelioma in multiple spinal levels without skin changes. ( Bradeen, HA; Kalof, AN; Lisle, JW, 2009) |
| "Portal hypertension was induced by partial ligation of the portal vein (PVL)." | 1.29 | Thalidomide inhibits tumor necrosis factor alpha, decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal-hypertensive rats. ( Cadelina, G; Groszmann, RJ; Lopez-Talavera, JC; Merrill, W; Olchowski, J, 1996) |
| "A new case of Tetraphocomelia--cleft palatee syndrome is described." | 1.25 | The tetraphocomelia -- cleft palate syndrome: description of a new case. ( Grosse, FR; Pandel, C; Wiedemann, HR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (68.18) | 18.7374 |
| 1990's | 5 (7.58) | 18.2507 |
| 2000's | 10 (15.15) | 29.6817 |
| 2010's | 4 (6.06) | 24.3611 |
| 2020's | 2 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Banday, AZ | 1 |
| Joshi, V | 1 |
| Arora, K | 1 |
| Sadanand, R | 1 |
| Basu, S | 1 |
| Pilania, RK | 1 |
| Jindal, AK | 1 |
| Vignesh, P | 1 |
| Gupta, A | 1 |
| Sharma, S | 1 |
| Dhaliwal, M | 1 |
| Rawat, A | 1 |
| Singh, S | 1 |
| Suri, D | 1 |
| Martinez-Lopez, A | 1 |
| Salvador-Rodriguez, L | 1 |
| Montero-Vilchez, T | 1 |
| Molina-Leyva, A | 1 |
| Tercedor-Sanchez, J | 1 |
| Arias-Santiago, S | 1 |
| Takama, H | 1 |
| Ando, Y | 1 |
| Yanagishita, T | 1 |
| Ohshima, Y | 1 |
| Akiyama, M | 1 |
| Watanabe, D | 1 |
| Soriano, A | 1 |
| Soriano, M | 1 |
| Espinosa, G | 1 |
| Manna, R | 1 |
| Emmi, G | 1 |
| Cantarini, L | 1 |
| Hernández-Rodríguez, J | 1 |
| Devos, T | 1 |
| Thiessen, S | 1 |
| Cuyle, PJ | 1 |
| Meersseman, W | 1 |
| Delforge, M | 1 |
| Zhang, L | 1 |
| Au, S | 1 |
| Aronson, IK | 1 |
| Cazzola, M | 1 |
| Tassinari, D | 1 |
| Santelmo, C | 1 |
| Tombesi, P | 1 |
| Sartori, S | 1 |
| Lisle, JW | 1 |
| Bradeen, HA | 1 |
| Kalof, AN | 1 |
| Aue, G | 1 |
| Njuguna, N | 1 |
| Tian, X | 1 |
| Soto, S | 1 |
| Hughes, T | 1 |
| Vire, B | 1 |
| Keyvanfar, K | 1 |
| Gibellini, F | 1 |
| Valdez, J | 1 |
| Boss, C | 1 |
| Samsel, L | 1 |
| McCoy, JP | 1 |
| Wilson, WH | 1 |
| Pittaluga, S | 1 |
| Wiestner, A | 1 |
| SCHEID, W | 1 |
| WIECK, HH | 1 |
| STAMMLER, A | 1 |
| KLADETZKY, A | 1 |
| GIBBELS, E | 1 |
| BERGSTROM, AL | 1 |
| NILSSON, L | 1 |
| PETTERSSON, G | 1 |
| SODERLING, B | 1 |
| VICTORIN, L | 1 |
| WINBERG, J | 1 |
| TAUSSIG, HB | 1 |
| MAY, C | 1 |
| FARIZON, F | 1 |
| MASBERNARD, A | 1 |
| HIRSCH, M | 1 |
| SCHONENBERG, H | 1 |
| WEICKER, H | 6 |
| BACHMANN, KD | 3 |
| PFEIFFER, RA | 3 |
| GLEISS, J | 3 |
| HUNGERLAND, H | 1 |
| CUTHBERT, R | 1 |
| SPEIRS, AL | 1 |
| DALGAARD, JB | 1 |
| KASS, E | 1 |
| PINCHERLE, M | 1 |
| GAROFANO, I | 1 |
| RAVAILLE, G | 1 |
| METZ, J | 1 |
| MAUER, ML | 1 |
| TORRICELLI, C | 1 |
| MATTURRI, L | 1 |
| NODARI, R | 1 |
| MAUSS, HJ | 1 |
| VOGL, A | 1 |
| ROSEN, E | 1 |
| DELAHUNT, CS | 1 |
| LASSEN, LJ | 1 |
| SCHMIDT, JG | 1 |
| LAMB, DW | 1 |
| SIMPSON, DC | 1 |
| SCHUTT, WH | 1 |
| SPEIRS, NT | 1 |
| SUNDERLAND, G | 1 |
| BAKER, G | 1 |
| MAIER, WA | 1 |
| ERFURTH, F | 1 |
| MCCOLL, JD | 1 |
| GLOBUS, M | 1 |
| ROBINSON, S | 1 |
| SACHTLEBEN, P | 1 |
| BLAES, R | 1 |
| KENEZ, J | 1 |
| LENZ, W | 2 |
| KNAPP, K | 2 |
| Varella, TC | 1 |
| Nishimura, MY | 1 |
| Machado, MC | 1 |
| de Moraes-Vasconcelos, D | 1 |
| Rivitti, EA | 1 |
| Strauss, RM | 1 |
| Bäte, J | 1 |
| Nischal, KK | 1 |
| Clayton, T | 1 |
| Gooi, J | 1 |
| Darling, JC | 1 |
| Newton-Bishop, JA | 1 |
| Marque, M | 1 |
| Guillot, B | 1 |
| Bessis, D | 1 |
| Bölke, E | 1 |
| Gripp, S | 1 |
| Peiper, M | 1 |
| Budach, W | 1 |
| Schwarz, A | 1 |
| Orth, K | 1 |
| Reinecke, P | 1 |
| van de Nes, JA | 1 |
| Thornburg, A | 1 |
| Abonour, R | 1 |
| Smith, P | 1 |
| Knox, K | 1 |
| Twigg, HL | 1 |
| Van Regemorter, N | 1 |
| Haumont, D | 1 |
| Kirkpatrick, C | 1 |
| Viseur, P | 1 |
| Jeanty, P | 1 |
| Dodion, J | 1 |
| Milaire, J | 1 |
| Rooze, M | 1 |
| Rodesch, F | 1 |
| Miller, MT | 1 |
| Lopez-Talavera, JC | 1 |
| Cadelina, G | 1 |
| Olchowski, J | 1 |
| Merrill, W | 1 |
| Groszmann, RJ | 1 |
| Jacobsson, C | 1 |
| Granström, G | 1 |
| Drenth, JP | 1 |
| Vonk, AG | 1 |
| Simon, A | 1 |
| Powell, R | 1 |
| van der Meer, JW | 1 |
| Waring, GO | 1 |
| Shields, JA | 1 |
| Grosse, FR | 2 |
| Wiedemann, H | 1 |
| Calnan, CD | 1 |
| Meara, RH | 1 |
| Schaller, A | 1 |
| Sheskin, J | 1 |
| Pandel, C | 1 |
| Wiedemann, HR | 1 |
| McCredie, J | 1 |
| Smithells, RW | 1 |
| Newman, CG | 1 |
| Hendrickx, AG | 1 |
| Phelps, PD | 1 |
| Elsahy, NI | 1 |
| Paulsen, K | 1 |
| Warburg, M | 1 |
7 reviews available for thalidomide and Syndrome
| Article | Year |
|---|---|
Challenges in the diagnosis of periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome in developing countries-A decade of experience from North India.
Topics: Antipyretics; Antiviral Agents; Child; Colchicine; Developing Countries; Fever; Humans; Lymphadeniti | 2022 |
Vascular malformations syndromes: an update.
Topics: Abnormalities, Multiple; Bevacizumab; Class I Phosphatidylinositol 3-Kinases; Growth Disorders; Huma | 2019 |
Current Therapeutic Options for the Main Monogenic Autoinflammatory Diseases and PFAPA Syndrome: Evidence-Based Approach and Proposal of a Practical Guide.
Topics: Animals; Autoimmune Diseases; Biological Therapy; Colchicine; Dapsone; Evidence-Based Medicine; Feve | 2020 |
[THALIDOMIDE EMBRYOPATHY. SURVEY AND PATHOGENIC MECHANISM].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Data Collection; Ectromelia; Embryology; Fetal | 1963 |
Ocular anomalies: embryological implications.
Topics: Abnormalities, Multiple; Eye Abnormalities; Humans; Syndrome; Teratology; Thalidomide | 1995 |
Syndromes with reduction and surplus anomalies of the hand.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fanconi Syndrome; Female; Fingers; Hand Deform | 1977 |
The heterogeneity of microphthalmia in the mentally retarded.
Topics: Abnormalities, Multiple; Abortifacient Agents; Adolescent; Adult; Brain Injuries; Child, Preschool; | 1971 |
3 trials available for thalidomide and Syndrome
| Article | Year |
|---|---|
Thalidomide in the treatment of cancer cachexia.
Topics: Aged; Angiogenesis Inhibitors; Anorexia; Cachexia; Drug Monitoring; Female; Gastrointestinal Neoplas | 2008 |
Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia.
Topics: Aged; Antineoplastic Agents; B7-1 Antigen; Cytokines; Female; Humans; Lenalidomide; Leukemia, Lympho | 2009 |
Limited efficacy of thalidomide in the treatment of febrile attacks of the hyper-IgD and periodic fever syndrome: a randomized, double-blind, placebo-controlled trial.
Topics: Acute-Phase Reaction; Adult; Cross-Over Studies; Cytokines; DNA Mutational Analysis; Double-Blind Me | 2001 |
56 other studies available for thalidomide and Syndrome
| Article | Year |
|---|---|
Successful treatment of pustulotic arthro-osteitis with apremilast: a case report with follow-up MRI.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Female; Follow-Up Studies; Humans; Magneti | 2019 |
Long-term follow-up in a patient with the dermato-neuro syndrome treated with high-dose melphalan, thalidomide, and intravenous immunoglobulins for more than 7 years.
Topics: Adult; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Male; Melphalan; Nervous System Dise | 2014 |
Successful long-term thalidomide therapy for discoid lupus erythematosus-lichen planus overlap syndrome.
Topics: Adult; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Lichen Planus; Lupus | 2014 |
Myelodysplastic syndrome with isolated 5q deletion (5q- syndrome). A clonal stem cell disorder characterized by defective ribosome biogenesis.
Topics: Adult; Blood Platelets; Chemistry, Pharmaceutical; Chromosome Deletion; Chromosomes, Human, Pair 5; | 2008 |
Kaposiform hemangioendothelioma in multiple spinal levels without skin changes.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Tumor; Celecoxib; Chil | 2009 |
[Polyneuritic syndrome after prolonged thalidomide medication].
Topics: Hypnotics and Sedatives; Neuritis; Syndrome; Thalidomide | 1961 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome | 1962 |
A study of the German outbreak of phocomelia. The thalidomide syndrome.
Topics: Disease Outbreaks; Ectromelia; Ethnicity; Humans; Hypnotics and Sedatives; Syndrome; Thalidomide | 1962 |
[Contribution to dysmelia syndrome].
Topics: Extremities; Humans; Syndrome; Thalidomide | 1962 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1962 |
[Chromosomal studies on so-called thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
Thalidomide embryopathy.
Topics: Abnormalities, Multiple; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Ectromelia; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[Thalidomide embryopathy. II. Results of individual anamnestic findings in the areas of inquiry of the universities of Bonn, Cologne, Muenster and Duesseldorf pediatric clinics].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Research; Syndrome; Thalidomide; | 1962 |
[Thalidomide embryopathy. I. Incidence inside and outside Germany].
Topics: Fetal Diseases; Germany; Hypnotics and Sedatives; Incidence; Syndrome; Thalidomide | 1962 |
Thalidomide induced malformations--a radiological survey.
Topics: Abnormalities, Multiple; Congenital Abnormalities; Data Collection; Radiology; Syndrome; Thalidomide | 1963 |
[Thalidomide syndrome without dysmelia. A case with a rare congenital heart lesion].
Topics: Heart; Heart Defects, Congenital; Humans; Syndrome; Thalidomide | 1963 |
[THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Multiple; Fetal Diseases; Humans; Syndrome; Thalidomide | 1963 |
[PHOCOMELIA SYNDROME CAUSED BY THALIDOMIDE].
Topics: Ectromelia; Female; Infant, Newborn; Pregnancy; Pregnancy Complications; Radiography; Syndrome; Thal | 1963 |
[1ST CASE OF THALIDOMIDE EMBRYOPATHY STUDIED IN FRANCE].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ectromelia; Fetal Diseases; France; Infant, Ne | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. 3].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
[THALIDOMIDE EMBRYOPATHY IN ITALY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Italy; Statistics as Topic; Sy | 1963 |
[THALIDOMIDE EMBRYOPATHIES IN MILANO AND SUBURBS. ANATOMO-CLINICAL STUDY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Biomedical Research; Ectromelia; Fetal Disease | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. III].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
[DRUG USE DURING PREGNANCY AFTER DISCOVERY OF THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Ectromelia; Female; | 1964 |
[THALIDOMIDE SYNDROME AND THE TREATMENT OF THALIDOMIDE CASES].
Topics: Abnormalities, Drug-Induced; Hand Deformities; Infant, Newborn; Pregnancy; Syndrome; Thalidomide; To | 1964 |
THALIDOMIDE SYNDROME IN MONKEYS.
Topics: Abnormalities, Drug-Induced; Animals; Embryo Implantation; Extremities; Female; Fetus; Haplorhini; H | 1964 |
[OCULOMOTOR PARALYSIS IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Female; Fetal Diseases; Ophthalmoplegia | 1964 |
THE MANAGEMENT OF UPPER LIMB DEFICIENCIES IN THE THALIDOMIDE-TYPE SYNDROME.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Disease Management; Prostheses and Implants; Syndrome | 1965 |
THALIDOMIDE EMBRYOPATHY AND LIMB DEFECTS; ESPERIENCES IN HABILITATION OF CHILDREN WITH ECTROMELIAS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Angiography; Artificial Limbs; Child; Ectromel | 1965 |
[ROENTGENOLOGIC CHANGES IN RABBIT THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Carbon Tetrachloride; Ectromelia; Fet | 1965 |
AN ATTEMPTED REVERSAL OF THALIDOMIDE EMBRYOPATHY IN THE RAT BY GLUTAMINE.
Topics: Abnormalities, Drug-Induced; Fetal Diseases; Glutamates; Glutamine; Pathology; Pharmacology; Pregnan | 1965 |
[SIMILARITIES AND PECULIARITIES OF FANCONI'S ANEMIA AND THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Multiple; Anemia; Anemia, Aplastic; Diagnosis, Differential; Ectromelia; Fanconi Anem | 1964 |
[THE OCCURENCE OF DYSMELIA SYNDROMES IN THE SAAR REGION].
Topics: Abnormalities, Drug-Induced; Biometry; Germany; Germany, West; Infant, Newborn; Statistics as Topic; | 1965 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Extremities; Fetal Diseases; Hypnotics and Sedatives; Limb Deformities, Con | 1962 |
Thalidomide embryopathy.
Topics: Abnormalities, Multiple; Extremities; Fetal Diseases; Hypnotics and Sedatives; Limb Deformities, Con | 1962 |
[Thalidomide embryopathy].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome; Thalidomide | 1962 |
Schnitzler's syndrome without monoclonal gammopathy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Diagnosis, Differential; Drug Therapy, C | 2005 |
A child with laryngo-onychocutaneous syndrome partially responsive to treatment with thalidomide.
Topics: Adolescent; Conjunctival Diseases; Epidermolysis Bullosa; Female; Humans; Immunosuppressive Agents; | 2006 |
Thalidomide for treatment of PFAPA syndrome.
Topics: Adult; Fever; Humans; Immunosuppressive Agents; Lymphadenitis; Male; Periodicity; Pharyngitis; Recur | 2007 |
Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon.
Topics: Angiogenesis Inhibitors; Diagnosis, Differential; Fatal Outcome; Hemangioendothelioma, Epithelioid; | 2006 |
Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide.
Topics: Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Dexamethasone; Drug Therapy, Combination; Dys | 2007 |
Holt Oram syndrome mistaken for thalidomide embryopathy--embryological considerations.
Topics: Abnormalities, Drug-Induced; Adult; Diagnosis, Differential; Ectromelia; Female; Genetic Counseling; | 1982 |
Thalidomide inhibits tumor necrosis factor alpha, decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal-hypertensive rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Hemodynamics; Hypertension, Portal; Male; Nitric Ox | 1996 |
Clinical appearance of spontaneous and induced first and second branchial arch syndromes.
Topics: Adult; Animals; Branchial Region; Craniofacial Dysostosis; Disease Models, Animal; Facial Asymmetry; | 1997 |
Partial unilateral cryptophthalmos with syndactyly, brachycephaly, and renal anomalies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child, Preschool; Eye Abnormalities; Eyelids; | 1975 |
Actinic prurigo (Hutchinson's summer prurigo).
Topics: Adult; Diagnosis, Differential; Female; Humans; Male; Photosensitivity Disorders; Prurigo; Seasons; | 1977 |
[Epidemiology of congenital abnormalities].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Epidemiologic Method | 1977 |
[Treatment of prurigo nodularis Hyde using thalidomide].
Topics: Eczema; Female; Humans; Middle Aged; Prurigo; Syndrome; Thalidomide | 1975 |
The tetraphocomelia -- cleft palate syndrome: description of a new case.
Topics: Abnormalities, Multiple; Arm; Child, Preschool; Cleft Palate; Diagnosis, Differential; Ectromelia; F | 1975 |
Comments on "Reply to 'Comments on "Moebius syndrome: animal model--human correlations and evidence for a brainstem vascular etiology"'".
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Brain Stem; Female; Humans; Pregnancy; Syndrom | 1992 |
Recognition of thalidomide defects.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Diagnosis, Differential; Head; Humans; Limb De | 1992 |
The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis).
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Coccyx; Female; Femur; Fingers; Gestatio | 1973 |
Congenital lesions of the inner ear, demonstrated by tomography.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Child; Cochlea; Ear; Ear, I | 1974 |
Moebius syndrome associated with the mother taking thalidomide during gestation. Case report.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Anxiety; Facial Expression; Fa | 1973 |
Otological features in exomphalos-macro-glossia-gigantism syndrome (Wiedemann's syndrome).
Topics: Abnormalities, Drug-Induced; Adolescent; Audiometry; Deafness; Female; Gigantism; Hernia, Umbilical; | 1973 |