thalidomide has been researched along with Syncope in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both thalidomide and atenolol have been reported to cause bradycardia." | 5.35 | Syncope and sinus bradycardia from combined use of thalidomide and beta-blocker. ( Yamaguchi, T, 2008) |
| "Both thalidomide and atenolol have been reported to cause bradycardia." | 1.35 | Syncope and sinus bradycardia from combined use of thalidomide and beta-blocker. ( Yamaguchi, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Lazzari, M | 1 |
| Fedrigo, M | 1 |
| Migliore, F | 1 |
| Cianci, A | 1 |
| Cacciavillani, L | 1 |
| Tarantini, G | 1 |
| Giorgi, B | 1 |
| Iliceto, S | 1 |
| Thiene, G | 1 |
| Valente, M | 1 |
| Angelini, A | 1 |
| Adami, F | 1 |
| Perazzolo Marra, M | 1 |
| Yamaguchi, T | 1 |
2 other studies available for thalidomide and Syncope
| Article | Year |
|---|---|
Nonamyloidotic Light Chain Cardiomyopathy: The Arrhythmogenic Magnetic Resonance Pattern.
Topics: Bortezomib; Cardiomyopathies; Combined Modality Therapy; Defibrillators, Implantable; Dexamethasone; | 2016 |
Syncope and sinus bradycardia from combined use of thalidomide and beta-blocker.
Topics: Adrenergic beta-Antagonists; Aged; Bradycardia; Drug Therapy, Combination; Heart Rate; Humans; Male; | 2008 |