thalidomide has been researched along with Strabismus in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Strabismus: Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A previous study of 86 thalidomide-affected subjects with ophthalmic manifestations revealed the unexpected finding of autism in 4 of the 5 severely retarded individuals." | 3.70 | The puzzle of autism: an ophthalmologic contribution. ( Gillberg, C; Johansson, M; Miller, MT; Nilsson, EW; Strömland, K, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strömland, K | 2 |
| Miller, MT | 2 |
| Gillberg, C | 1 |
| Johansson, M | 1 |
| Nilsson, EW | 1 |
| Rafuse, EV | 1 |
| Arstikaitis, M | 1 |
| Brent, HP | 1 |
3 other studies available for thalidomide and Strabismus
| Article | Year |
|---|---|
Thalidomide embryopathy: revisited 27 years later.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Duane Retraction Syndrome; Eye Abnormal | 1993 |
The puzzle of autism: an ophthalmologic contribution.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Autistic Disorder; Child; Eye Diseases; Facial Paral | 1998 |
Ocular findings in thalidomide children.
Topics: Abnormalities, Drug-Induced; Blepharoptosis; Canada; Coloboma; Eye Abnormalities; Female; Humans; In | 1967 |