thalidomide has been researched along with Spondylarthropathies in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Spondylarthropathies: Heterogeneous group of arthritic diseases sharing clinical and radiologic features. They are associated with the HLA-B27 ANTIGEN and some with a triggering infection. Most involve the axial joints in the SPINE, particularly the SACROILIAC JOINT, but can also involve asymmetric peripheral joints. Subsets include ANKYLOSING SPONDYLITIS; REACTIVE ARTHRITIS; PSORIATIC ARTHRITIS; and others.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Mens, LJJ | 1 |
| van de Sande, MGH | 1 |
| Baeten, DLP | 1 |
| Krause, A | 1 |
| Märker-Hermann, E | 1 |
| Kehl, AS | 1 |
| Corr, M | 1 |
| Weisman, MH | 1 |
| Sieper, J | 1 |
| Lin, RJ | 1 |
| Curran, JJ | 1 |
| Zimmerman, TM | 1 |
| Song, J | 1 |
| Niewold, TB | 1 |
| Sweiss, NJ | 1 |
4 reviews available for thalidomide and Spondylarthropathies
| Article | Year |
|---|---|
New treatment paradigms in spondyloarthritis.
Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, | 2018 |
[Spondyloarthritis including psoriatic arthritis].
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Certolizumab Pegol; Comorbidity | 2014 |
Review: Enthesitis: New Insights Into Pathogenesis, Diagnostic Modalities, and Treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Autoimmunity; Bone Morphogen | 2016 |
New treatment targets for axial spondyloarthritis.
Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, | 2016 |
1 other study available for thalidomide and Spondylarthropathies
| Article | Year |
|---|---|
Lenalidomide for the treatment of cryoglobulinemia and undifferentiated spondyloarthropathy in a patient with multiple myeloma.
Topics: Adult; Antineoplastic Agents; Cryoglobulinemia; HLA-B27 Antigen; Humans; Lenalidomide; Lumbar Verteb | 2010 |