thalidomide has been researched along with Skin Ulcer in 12 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Skin Ulcer: An ULCER of the skin and underlying tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)." | 9.22 | Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022) |
| "We report a case of recalcitrant type I cryoglobulinemia treated successfully with long-term plasmapheresis in conjunction with thalidomide and dexamethasone." | 7.80 | Long-term plasmapheresis in conjunction with thalidomide and dexamethasone for the treatment of cutaneous ulcers and neovascular glaucoma in recalcitrant type I cryoglobulinemia. ( Churchill, WH; Qureshi, AA; Saavedra, AP; Yang, CH, 2014) |
| "This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)." | 5.22 | Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022) |
| "We report a case of recalcitrant type I cryoglobulinemia treated successfully with long-term plasmapheresis in conjunction with thalidomide and dexamethasone." | 3.80 | Long-term plasmapheresis in conjunction with thalidomide and dexamethasone for the treatment of cutaneous ulcers and neovascular glaucoma in recalcitrant type I cryoglobulinemia. ( Churchill, WH; Qureshi, AA; Saavedra, AP; Yang, CH, 2014) |
| "We report two cases of severe leg ulcerations in patients being treated with thalidomide for graft-versus-host disease following bone marrow transplantation." | 3.71 | Severe cutaneous ulceration following treatment with thalidomide for GVHD. ( Herman, J; Klumpp, T; Mangan, K; Sabol, P; Schlossberg, H, 2001) |
| "Thalidomide alone (200-300 mg daily) or associated with colchicine (2-3 mg daily) was given orally to 25 patients with aphthosis: 8 patients with recurrent oral aphthae; 4 patients with recurrent mucocutaneous aphthosis, without visceral involvement, and 13 patients with Behçet's disease (Touraine's aphthosis)." | 3.67 | [Treatment of aphthosis with thalidomide and with colchicine]. ( Faure, M; Genvo, MF; Thivolet, J, 1984) |
| "All patients had oral and genital aphthae, and 22 of 25 patients had cutaneous lesions consistent with Behçet's disease." | 1.29 | Behçet's disease. Report of twenty-five patients from the United States with prominent mucocutaneous involvement. ( Jorizzo, JL; Mangelsdorf, HC; White, WL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Iizuka, Y | 1 |
| Takase-Minegishi, K | 1 |
| Hirahara, L | 1 |
| Kirino, Y | 1 |
| Soejima, Y | 1 |
| Namkoong, HO | 1 |
| Horita, N | 1 |
| Yoshimi, R | 1 |
| Takeuchi, M | 1 |
| Takeno, M | 1 |
| Mizuki, N | 1 |
| Nakajima, H | 1 |
| Khammar, Z | 1 |
| Ouazzani, M | 1 |
| Bennani, B | 1 |
| Oubelkacem, N | 1 |
| Berrady, R | 1 |
| Yang, CH | 1 |
| Qureshi, AA | 1 |
| Churchill, WH | 1 |
| Saavedra, AP | 1 |
| Kamble, RT | 1 |
| Scholoff, A | 1 |
| Obi, AG | 1 |
| Heslop, HE | 1 |
| Brenner, MK | 1 |
| Carrum, G | 1 |
| Taraborelli, M | 1 |
| Monari, P | 1 |
| Cavazzana, I | 1 |
| Gualdi, G | 1 |
| Calzavara-Pinton, P | 1 |
| Franceschini, F | 1 |
| Cozzani, E | 1 |
| Gasparini, G | 1 |
| Parodi, A | 1 |
| Li, KY | 1 |
| Hu, YM | 1 |
| Lü, JB | 1 |
| Genvo, MF | 1 |
| Faure, M | 1 |
| Thivolet, J | 1 |
| Torras, H | 2 |
| Lecha, M | 2 |
| Mascaro, JM | 2 |
| Mangelsdorf, HC | 1 |
| White, WL | 1 |
| Jorizzo, JL | 1 |
| Schlossberg, H | 1 |
| Klumpp, T | 1 |
| Sabol, P | 1 |
| Herman, J | 1 |
| Mangan, K | 1 |
2 reviews available for thalidomide and Skin Ulcer
| Article | Year |
|---|---|
Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis.
Topics: Arthritis; Behcet Syndrome; Genitalia; Humans; Oral Ulcer; Skin Ulcer; Thalidomide; Ulcer | 2022 |
Pyoderma gangrenosum: a systematic review.
Topics: Anti-Inflammatory Agents; Arthritis; Dermatologic Agents; Diagnosis, Differential; Disease Progressi | 2014 |
1 trial available for thalidomide and Skin Ulcer
| Article | Year |
|---|---|
Thalidomide treatment of recurrent necrotic giant mucocutaneous aphthae and aphthosis.
Topics: Behcet Syndrome; Humans; Recurrence; Skin Ulcer; Thalidomide | 1982 |
9 other studies available for thalidomide and Skin Ulcer
| Article | Year |
|---|---|
[Digital ischemia revealing multiple myeloma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cryoglobulinemia; Dexamethasone; F | 2018 |
Long-term plasmapheresis in conjunction with thalidomide and dexamethasone for the treatment of cutaneous ulcers and neovascular glaucoma in recalcitrant type I cryoglobulinemia.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents; Combined Modality Therapy; Cryoglobulinemia; Dexa | 2014 |
Neuropathic dermatomes and cutaneous ulceration in patients with chronic GVHD.
Topics: Bone Marrow Transplantation; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukem | 2014 |
Severe skin involvement in type II cryoglobulinemia successfully treated with thalidomide.
Topics: Aged; Cryoglobulinemia; Humans; Immunosuppressive Agents; Male; Skin Diseases; Skin Ulcer; Thalidomi | 2015 |
[Six years relapse-free treatment of a case with Langerhans cell histiocytosis grade III treated with thalidomide and prednisone].
Topics: Administration, Oral; Adolescent; Female; Histiocytosis, Langerhans-Cell; Humans; Lymph Nodes; Predn | 2012 |
[Treatment of aphthosis with thalidomide and with colchicine].
Topics: Adult; Behcet Syndrome; Colchicine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Sk | 1984 |
Behçet's disease. Report of twenty-five patients from the United States with prominent mucocutaneous involvement.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Behcet Syndrome; Colchic | 1996 |
Severe cutaneous ulceration following treatment with thalidomide for GVHD.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modalit | 2001 |
Thalidomide in the treatment of recurrent, necrotic, and giant mucocutaneous aphthae and aphthosis.
Topics: Adult; Behcet Syndrome; Humans; Male; Recurrence; Skin Ulcer; Stomatitis, Aphthous; Thalidomide | 1979 |