Page last updated: 2024-11-05

thalidomide and Silicosis

thalidomide has been researched along with Silicosis in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Silicosis: A form of pneumoconiosis resulting from inhalation of dust containing crystalline form of SILICON DIOXIDE, usually in the form of quartz. Amorphous silica is relatively nontoxic.

Research Excerpts

ExcerptRelevanceReference
"Silicosis is the most prevalent occupational disease in China."5.72Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway. ( Cai, W; Jin, F; Li, T; Li, Y; Liu, H; Liu, W; Wang, X; Xu, H; Yang, F; Yang, X, 2022)
"Silicosis is the most prevalent occupational disease in China."1.72Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway. ( Cai, W; Jin, F; Li, T; Li, Y; Liu, H; Liu, W; Wang, X; Xu, H; Yang, F; Yang, X, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Li, Y1
Cai, W1
Jin, F1
Wang, X1
Liu, W1
Li, T1
Yang, X1
Liu, H1
Xu, H1
Yang, F1

Other Studies

1 other study available for thalidomide and Silicosis

ArticleYear
Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway.
    International journal of molecular sciences, 2022, May-18, Volume: 23, Issue:10

    Topics: Animals; Mice; NF-kappa B; Pulmonary Fibrosis; Silicon Dioxide; Silicosis; Thalidomide; Toll-Like Re

2022