thalidomide has been researched along with Sicca Syndrome in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lenalidomide therapy was started after the diagnosis and the patient had a favorable outcome." | 1.46 | Utility of osteosclerotic lesion biopsy in diagnosis of POEMS syndrome: A case report. ( Akiyama, H; Hara, D; Hasegawa, Y; Hoshikawa, M; Nukui, S; Shimizu, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hara, D | 1 |
| Akiyama, H | 1 |
| Nukui, S | 1 |
| Shimizu, T | 1 |
| Hoshikawa, M | 1 |
| Hasegawa, Y | 1 |
| Pillemer, SR | 1 |
| Leakan, RA | 2 |
| Sankar, V | 2 |
| Manny, J | 1 |
| Baum, BJ | 1 |
| Smith, J | 1 |
| Chaudhry, U | 1 |
| Fox, PC | 1 |
| Radfar, L | 1 |
| Ligier, S | 1 |
| Brennan, MT | 1 |
| Moutsopoulos, NM | 1 |
| Angelov, N | 1 |
| Pillemer, S | 1 |
| Wahl, SM | 1 |
2 trials available for thalidomide and Sicca Syndrome
| Article | Year |
|---|---|
Prominent adverse effects of thalidomide in primary Sjögren's syndrome.
Topics: Double-Blind Method; Drug Administration Schedule; Humans; Immunosuppressive Agents; Sjogren's Syndr | 2004 |
Immunological consequences of thalidomide treatment in Sjögren's syndrome.
Topics: Cytokines; Double-Blind Method; Female; Humans; Immunophenotyping; Immunosuppressive Agents; Leukocy | 2006 |
1 other study available for thalidomide and Sicca Syndrome
| Article | Year |
|---|---|
Utility of osteosclerotic lesion biopsy in diagnosis of POEMS syndrome: A case report.
Topics: Arthritis, Rheumatoid; Cell Proliferation; Diagnosis, Differential; Female; Humans; Immunoelectropho | 2017 |