Page last updated: 2024-11-05

thalidomide and Shingles

thalidomide has been researched along with Shingles in 4 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"The incidence of herpes zoster is substantial during bortezomib treatment in patients with multiple myeloma (MM)."7.81Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy. ( Choe, PG; Kim, BS; Kim, I; Kim, JW; Koh, Y; Kwon, JH; Min, CK; Mun, YC; Nam, SH; Park, WB; Park, Y, 2015)
" We present a case of coinfection with disseminated HSV and VZV infection in a patient taking thalidomide for relapsed multiple myeloma."7.71Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma. ( Curley, MJ; Hassoun, PM; Hussein, SA, 2002)
"The incidence of herpes zoster is substantial during bortezomib treatment in patients with multiple myeloma (MM)."3.81Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy. ( Choe, PG; Kim, BS; Kim, I; Kim, JW; Koh, Y; Kwon, JH; Min, CK; Mun, YC; Nam, SH; Park, WB; Park, Y, 2015)
" We present a case of coinfection with disseminated HSV and VZV infection in a patient taking thalidomide for relapsed multiple myeloma."3.71Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma. ( Curley, MJ; Hassoun, PM; Hussein, SA, 2002)
" Thalidomide (Synovir), developed by Celgene, has received limited approval for the treatment of leprosy."3.70FDA approves fomivirsen, famciclovir, and Thalidomide. Food and Drug Administration. ( Highleyman, L, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
König, C1
Kleber, M1
Reinhardt, H1
Knop, S1
Wäsch, R1
Engelhardt, M1
Kim, JW1
Min, CK1
Mun, YC1
Park, Y1
Kim, BS1
Nam, SH1
Koh, Y1
Kwon, JH1
Choe, PG1
Park, WB1
Kim, I1
Highleyman, L1
Curley, MJ1
Hussein, SA1
Hassoun, PM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Immune Response Induced by Zoster Vaccine According to the Timing of Vaccination After Zoster Illness[NCT02704572]60 participants (Actual)Interventional2016-03-31Completed
Comparison of Change in Humoral and Cellular Immunity Induced by Zoster Vaccine According to the Timing of Vaccination After Hematopoietic Stem Cell Transplantation[NCT03192319]86 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for thalidomide and Shingles

ArticleYear
Incidence, risk factors, and implemented prophylaxis of varicella zoster virus infection, including complicated varicella zoster virus and herpes simplex virus infections, in lenalidomide-treated multiple myeloma patients.
    Annals of hematology, 2014, Volume: 93, Issue:3

    Topics: Acyclovir; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibiotic Prophylaxis; Antiviral Agent

2014
Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 73

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bortezomib; Female; Herpes Zoster; Herpesviru

2015
Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 73

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bortezomib; Female; Herpes Zoster; Herpesviru

2015
Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 73

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bortezomib; Female; Herpes Zoster; Herpesviru

2015
Varicella-zoster virus-specific cell-mediated immunity and herpes zoster development in multiple myeloma patients receiving bortezomib- or thalidomide-based chemotherapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 73

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bortezomib; Female; Herpes Zoster; Herpesviru

2015
FDA approves fomivirsen, famciclovir, and Thalidomide. Food and Drug Administration.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: 2-Aminopurine; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; D

1998
Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma.
    Journal of clinical microbiology, 2002, Volume: 40, Issue:6

    Topics: Angiogenesis Inhibitors; Female; Herpes Simplex; Herpes Zoster; Humans; Middle Aged; Multiple Myelom

2002