thalidomide has been researched along with Retrolental Fibroplasia in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide is a well-known anti-angiogenic drug." | 5.35 | The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity. ( Katz, G; Pri-Chen, S; Rabinowitz, R; Rosner, M; Spierer, A, 2008) |
| "Thalidomide is a well-known anti-angiogenic drug." | 1.35 | The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity. ( Katz, G; Pri-Chen, S; Rabinowitz, R; Rosner, M; Spierer, A, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabinowitz, R | 1 |
| Katz, G | 1 |
| Rosner, M | 1 |
| Pri-Chen, S | 1 |
| Spierer, A | 1 |
| Silverman, WA | 1 |
2 other studies available for thalidomide and Retrolental Fibroplasia
| Article | Year |
|---|---|
The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity.
Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Dextrans; Disease Models, Animal; Fluoresceins; | 2008 |
Medical inflation.
Topics: Financing, Government; History, 20th Century; Humans; Infant Nutritional Physiological Phenomena; In | 1980 |