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thalidomide and Retinal Detachment

thalidomide has been researched along with Retinal Detachment in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klaas, D1
Schütte, E1
Lizin, F1
Schrader, KE1

Other Studies

2 other studies available for thalidomide and Retinal Detachment

ArticleYear
[Atypical retinal detachment in an adolescent with thalidomide abnormalities].
    Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1977, Volume: 74

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Female; Humans; Retinal Degenerati

1977
[Damages to the anterior eye segment by drugs].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1969, Volume: 1-3, Issue:1

    Topics: Anti-Bacterial Agents; Anticoagulants; Antidepressive Agents; Cornea; Dinitrophenols; Drug-Related S

1969