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thalidomide and Response Evaluation Criteria in Solid Tumors

thalidomide has been researched along with Response Evaluation Criteria in Solid Tumors in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Response Evaluation Criteria in Solid Tumors: An internationally recognized set of published rules used for evaluation of cancer treatment that define when tumors found in cancer patients improve, worsen, or remain stable during treatment. These criteria are based specifically on the response of the tumor(s) to treatment, and not on the overall health status of the patient resulting from treatment.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Said, R1
Kakadiaris, E1
Piha-Paul, S1
Fu, S1
Falchook, G1
Janku, F1
Wheler, JJ1
Zinner, R1
Hong, DS1
Kurzrock, R1
Tsimberidou, AM1

Trials

1 trial available for thalidomide and Response Evaluation Criteria in Solid Tumors

ArticleYear
Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer.
    Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colo

2016