thalidomide has been researched along with Pyloric Stenosis in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Pyloric Stenosis: Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a retrospective study of 832 cases of thalidomide embryopathy (ThE) between October 1, 1959 and July 31, 1962, a highly significant accumulation of cases with infantile hypertrophic pyloric stenosis (IHPS) was registrated." | 7.67 | Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide. ( Kramer, M; Schäfer, KH, 1987) |
| "In a retrospective study of 832 cases of thalidomide embryopathy (ThE) between October 1, 1959 and July 31, 1962, a highly significant accumulation of cases with infantile hypertrophic pyloric stenosis (IHPS) was registrated." | 3.67 | Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide. ( Kramer, M; Schäfer, KH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MATTURRI, L | 1 |
| NODARI, R | 1 |
| Schäfer, KH | 1 |
| Kramer, M | 1 |
2 other studies available for thalidomide and Pyloric Stenosis
| Article | Year |
|---|---|
[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE].
Topics: Appendix; Congenital Abnormalities; Ectromelia; Female; Fetal Diseases; Heart Defects, Congenital; H | 1963 |
Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide.
Topics: Female; Germany, West; Humans; Hypertrophy; Infant, Newborn; Male; Pyloric Stenosis; Retrospective S | 1987 |