thalidomide has been researched along with Pulmonary Sarcoidosis in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Limited data report thalidomide improves cutaneous sarcoidosis; no benefit has been reported for pulmonary localization." | 9.16 | Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. ( Antonelli, A; Barachini, P; Calabrese, R; Carpi, A; Cei, G; Cristofani, R; Fazzi, P; Manni, E; Piazza, S; Siciliano, G, 2012) |
| "To determine the benefit and corticosteroid-sparing potential of thalidomide in corticosteroid-dependent pulmonary sarcoidosis." | 9.12 | The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis. ( Byars, T; Cox, CE; Hartung, C; Judson, MA; Silvestri, J, 2006) |
| "We present the case of a 71-year-old woman with a long-standing history of refractory pulmonary sarcoidosis, who, upon commencement of treatment with lenalidomide for her newly diagnosed 5q-myelodysplastic syndrome, showed a remarkable, immediate, unexpected response and recovery of her sarcoidosis-related symptoms, improvement of her vital capacity, and complete clearance of her bibasal alveolor infiltrates." | 7.81 | Use of Lenalidomide in 5q-Myelodysplastic Syndrome Provides Novel Treatment Prospects in Management of Pulmonary Sarcoidosis. ( Bazargan, A; Giv, MJ; Yoosuff, A, 2015) |
| " Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy." | 7.69 | Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. ( Bonaccorsi, P; Calvieri, S; Carlesimo, M; Giustini, S; Rossi, A, 1995) |
| "Limited data report thalidomide improves cutaneous sarcoidosis; no benefit has been reported for pulmonary localization." | 5.16 | Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids. ( Antonelli, A; Barachini, P; Calabrese, R; Carpi, A; Cei, G; Cristofani, R; Fazzi, P; Manni, E; Piazza, S; Siciliano, G, 2012) |
| "To determine the benefit and corticosteroid-sparing potential of thalidomide in corticosteroid-dependent pulmonary sarcoidosis." | 5.12 | The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis. ( Byars, T; Cox, CE; Hartung, C; Judson, MA; Silvestri, J, 2006) |
| "We present the case of a 71-year-old woman with a long-standing history of refractory pulmonary sarcoidosis, who, upon commencement of treatment with lenalidomide for her newly diagnosed 5q-myelodysplastic syndrome, showed a remarkable, immediate, unexpected response and recovery of her sarcoidosis-related symptoms, improvement of her vital capacity, and complete clearance of her bibasal alveolor infiltrates." | 3.81 | Use of Lenalidomide in 5q-Myelodysplastic Syndrome Provides Novel Treatment Prospects in Management of Pulmonary Sarcoidosis. ( Bazargan, A; Giv, MJ; Yoosuff, A, 2015) |
| " Because administration of low doses of thalidomide has been successful in treating other inflammatory diseases, it was used in a patient with systemic sarcoidosis who was unresponsive to corticosteroids and in a patient with pulmonary sarcoidosis, in whom Kaposi's sarcoma developed after a course of corticosteroid therapy." | 3.69 | Treatment of cutaneous and pulmonary sarcoidosis with thalidomide. ( Bonaccorsi, P; Calvieri, S; Carlesimo, M; Giustini, S; Rossi, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giv, MJ | 2 |
| Yoosuff, A | 1 |
| Bazargan, A | 2 |
| Sahu, KK | 1 |
| Varma, SC | 1 |
| Bargagli, E | 1 |
| Olivieri, C | 1 |
| Rottoli, P | 1 |
| Fazzi, P | 1 |
| Manni, E | 1 |
| Cristofani, R | 1 |
| Cei, G | 1 |
| Piazza, S | 1 |
| Calabrese, R | 1 |
| Antonelli, A | 1 |
| Siciliano, G | 1 |
| Barachini, P | 1 |
| Carpi, A | 1 |
| Judson, MA | 1 |
| Silvestri, J | 1 |
| Hartung, C | 1 |
| Byars, T | 1 |
| Cox, CE | 1 |
| Carlesimo, M | 1 |
| Giustini, S | 1 |
| Rossi, A | 1 |
| Bonaccorsi, P | 1 |
| Calvieri, S | 1 |
1 review available for thalidomide and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Cytokine modulators in the treatment of sarcoidosis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; C | 2011 |
2 trials available for thalidomide and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Thalidomide for improving cutaneous and pulmonary sarcoidosis in patients resistant or with contraindications to corticosteroids.
Topics: Adult; Aged; Contraindications; Dose-Response Relationship, Drug; Drug Resistance; Feasibility Studi | 2012 |
The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis.
Topics: Adrenal Cortex Hormones; Black or African American; Drug Therapy, Combination; Female; Humans; Hydro | 2006 |
4 other studies available for thalidomide and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Use of Lenalidomide in 5q-Myelodysplastic Syndrome Provides Novel Treatment Prospects in Management of Pulmonary Sarcoidosis.
Topics: Aged; Anemia, Macrocytic; Chromosome Deletion; Chromosomes, Human, Pair 5; Female; Humans; Immunolog | 2015 |
Lenalidomide in Nonmalignant Disorders: A New Ray of Hope for Refractory Sarcoidosis.
Topics: Anemia, Macrocytic; Female; Humans; Immunologic Factors; Lung; Radiography; Sarcoidosis, Pulmonary; | 2015 |
Response.
Topics: Anemia, Macrocytic; Female; Humans; Immunologic Factors; Lung; Radiography; Sarcoidosis, Pulmonary; | 2015 |
Treatment of cutaneous and pulmonary sarcoidosis with thalidomide.
Topics: Aged; Female; Humans; Middle Aged; Sarcoidosis; Sarcoidosis, Pulmonary; Sarcoma, Kaposi; Skin Diseas | 1995 |