thalidomide has been researched along with Pregnancy in Diabetes in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the patterns of birth defects associated with diabetic embryopathy, a sensitivity-specificity analysis was performed on 4929 infants with major defects ascertained by the population-based Metropolitan Atlanta Congenital Defects Program between 1968 and 1980." | 1.28 | Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy. ( Becerra, JE; Cordero, JF; Erickson, JD; Khoury, MJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holmes, LB | 1 |
| HEYNE, D | 1 |
| Eriksson, UJ | 1 |
| Khoury, MJ | 1 |
| Becerra, JE | 1 |
| Cordero, JF | 1 |
| Erickson, JD | 1 |
| Wilson, JS | 1 |
| Vallance-Owen, J | 1 |
| Tuli, SM | 1 |
2 reviews available for thalidomide and Pregnancy in Diabetes
| Article | Year |
|---|---|
Teratogen-induced limb defects.
Topics: Chorionic Villi Sampling; Female; Humans; Limb Deformities, Congenital; Male; Misoprostol; Phenytoin | 2002 |
Certain causes of congenital malformations in Homo sapiens and their prevention.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Aminopterin; Antigen-Antibody Reactions; Chromos | 1967 |
4 other studies available for thalidomide and Pregnancy in Diabetes
| Article | Year |
|---|---|
[Initial statistical elements relative to congenital malformations in Belgium].
Topics: Belgium; Biometry; Congenital Abnormalities; Diabetes Mellitus; Female; Humans; Pregnancy; Pregnancy | 1963 |
Oxidative DNA damage and embryo development.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; DNA Damage; Embryonic and Fetal Development; Fem | 1999 |
Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Diabetes Mellitus, Type 1; Female; Georgia; H | 1989 |
Congenital deformities and insulin antagonism.
Topics: Carbohydrate Metabolism; Consanguinity; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; | 1966 |