thalidomide has been researched along with Pityriasis Rubra Pilaris in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Pityriasis Rubra Pilaris: A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maloney, NJ | 1 |
| Kim, MM | 1 |
| Nguyen, KA | 1 |
| Hisaw, LD | 1 |
| Worswick, S | 1 |
| Pellonnet, L | 1 |
| Beltzung, F | 1 |
| Franck, F | 1 |
| Rouanet, J | 1 |
| D'incan, M | 1 |
| Cho, M | 1 |
| Honda, T | 1 |
| Ueshima, C | 1 |
| Kataoka, T | 1 |
| Otsuka, A | 1 |
| Kabashima, K | 1 |
| Krase, IZ | 1 |
| Cavanaugh, K | 1 |
| Curiel-Lewandrowski, C | 1 |
4 other studies available for thalidomide and Pityriasis Rubra Pilaris
| Article | Year |
|---|---|
Patient experiences with biologics and apremilast in pityriasis rubra pilaris: A patient survey.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Drug Therapy, Combination; Female; Hum | 2019 |
A case of severe pityriasis rubra pilaris with a dramatic response to apremilast.
Topics: Dermatologic Agents; Humans; Male; Middle Aged; Phosphodiesterase 4 Inhibitors; Pityriasis Rubra Pil | 2018 |
A Case of Pityriasis Rubra Pilaris Treated Successfully with the Phosphodiesterase-4 Inhibitor Apremilast.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Middle Aged; Phosphodiesterase 4 Inhibitors | 2018 |
Treatment of Refractory Pityriasis Rubra Pilaris With Novel Phosphodiesterase 4 (PDE4) Inhibitor Apremilast.
Topics: Aged; Biopsy; Drug Resistance; Drug Substitution; Follow-Up Studies; Humans; Male; Phosphodiesterase | 2016 |