thalidomide has been researched along with Periodontal Diseases in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crohn's disease is a chronic inflammatory disease, which may involve any part of the gastrointestinal tract, including the oral cavity." | 2.41 | [Oral aspects of Crohn's disease]. ( Brand, HS; Scheper, HJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekfeldt, A | 1 |
| Carlsson, GE | 1 |
| Scheper, HJ | 1 |
| Brand, HS | 1 |
1 review available for thalidomide and Periodontal Diseases
| Article | Year |
|---|---|
[Oral aspects of Crohn's disease].
Topics: Crohn Disease; Dental Caries; Genetic Predisposition to Disease; Humans; Immunosuppressive Agents; O | 2000 |
1 other study available for thalidomide and Periodontal Diseases
| Article | Year |
|---|---|
Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.
Topics: Abnormalities, Drug-Induced; Anodontia; Dental Care for Disabled; Dental Caries; DMF Index; Female; | 2008 |