thalidomide has been researched along with Pemphigus in 9 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Pemphigus: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide (Tha) can be used as a selective treatment for mild pemphigus vulgaris (PV)." | 8.31 | Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88. ( Chen, J; Chen, M; Li, X; Lu, Z; Luan, C; Zhao, R, 2023) |
| "To determine whether apremilast, an inhibitor of the PDE4 normally used in psoriasis, may be of benefit in the blistering skin disorder pemphigus." | 7.96 | Case Report: Apremilast for Therapy-Resistant Pemphigus Vulgaris. ( Ghoreschi, K; Holstein, J; Meier, K; Solimani, F; Waschke, J, 2020) |
| "Pemphigus vegetans is a rare variant of pemphigus vulgaris." | 5.62 | Post-cesarean section pemphigus vegetans in a young woman treated with methylprednisolone and thalidomide. ( Jiang, L; Li, W; Qiu, X; Yuan, P, 2021) |
| "Thalidomide is a medication with strong anti-inflammatory, immunomodulatory, antiangiogenic, and sedative properties." | 5.56 | Thalidomide as a potential adjuvant treatment for paraneoplastic pemphigus: A single-center experience. ( Pan, M; Wang, J; Zhang, Y, 2020) |
| "Thalidomide (Tha) can be used as a selective treatment for mild pemphigus vulgaris (PV)." | 4.31 | Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88. ( Chen, J; Chen, M; Li, X; Lu, Z; Luan, C; Zhao, R, 2023) |
| "To determine whether apremilast, an inhibitor of the PDE4 normally used in psoriasis, may be of benefit in the blistering skin disorder pemphigus." | 3.96 | Case Report: Apremilast for Therapy-Resistant Pemphigus Vulgaris. ( Ghoreschi, K; Holstein, J; Meier, K; Solimani, F; Waschke, J, 2020) |
| "Pemphigus vegetans is a rare variant of pemphigus vulgaris." | 1.62 | Post-cesarean section pemphigus vegetans in a young woman treated with methylprednisolone and thalidomide. ( Jiang, L; Li, W; Qiu, X; Yuan, P, 2021) |
| "Thalidomide is a medication with strong anti-inflammatory, immunomodulatory, antiangiogenic, and sedative properties." | 1.56 | Thalidomide as a potential adjuvant treatment for paraneoplastic pemphigus: A single-center experience. ( Pan, M; Wang, J; Zhang, Y, 2020) |
| "Castleman disease is a rare lymphoproliferative disorder." | 1.35 | Successful immunomodulatory therapy in castleman disease with paraneoplastic pemphigus vulgaris. ( Gonda, A; Illes, A; Miltenyi, Z; Remenyik, E; Tar, I; Toth, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Luan, C | 1 |
| Lu, Z | 1 |
| Chen, J | 1 |
| Chen, M | 1 |
| Zhao, R | 1 |
| Li, X | 1 |
| Wang, J | 1 |
| Zhang, Y | 1 |
| Pan, M | 1 |
| Meier, K | 1 |
| Holstein, J | 1 |
| Solimani, F | 1 |
| Waschke, J | 1 |
| Ghoreschi, K | 1 |
| Qiu, X | 1 |
| Yuan, P | 1 |
| Li, W | 1 |
| Jiang, L | 1 |
| Miltenyi, Z | 1 |
| Toth, J | 1 |
| Gonda, A | 1 |
| Tar, I | 1 |
| Remenyik, E | 1 |
| Illes, A | 1 |
| Szturz, P | 1 |
| Adam, Z | 1 |
| Klincová, M | 1 |
| Feit, J | 1 |
| Krejčí, M | 1 |
| Pour, L | 1 |
| Zahradová, L | 1 |
| Vašků, V | 1 |
| Hájek, R | 1 |
| Mayer, J | 1 |
| Lee, FC | 1 |
| Cunha, PR | 1 |
| de Oliveira, JR | 1 |
| Salles, MJ | 1 |
| Jamora, J | 1 |
| Bystryn, JC | 1 |
| Schnitzler, L | 1 |
9 other studies available for thalidomide and Pemphigus
| Article | Year |
|---|---|
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
Topics: Acantholysis; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Caspase 3; HaCaT Cel | 2023 |
Thalidomide as a potential adjuvant treatment for paraneoplastic pemphigus: A single-center experience.
Topics: Humans; Neoplasm Recurrence, Local; Paraneoplastic Syndromes; Pemphigus; Prednisone; Thalidomide | 2020 |
Case Report: Apremilast for Therapy-Resistant Pemphigus Vulgaris.
Topics: Drug Resistance; Female; Humans; Middle Aged; Pemphigus; Phosphodiesterase 4 Inhibitors; Thalidomide | 2020 |
Post-cesarean section pemphigus vegetans in a young woman treated with methylprednisolone and thalidomide.
Topics: Autoimmune Diseases; Cesarean Section; Female; Humans; Methylprednisolone; Pemphigus; Pregnancy; Tha | 2021 |
Successful immunomodulatory therapy in castleman disease with paraneoplastic pemphigus vulgaris.
Topics: Adrenal Cortex Hormones; Castleman Disease; Cyclosporine; Female; Humans; Immunomodulation; Immunosu | 2009 |
Multiple myeloma associated IgA pemphigus: treatment with bortezomib- and lenalidomide-based regimen.
Topics: Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Female; Humans; Immunoglo | 2011 |
Longterm clinical remission of oral and cutaneous pemphigus with thalidomide.
Topics: Female; Humans; Immunosuppressive Agents; Lip Diseases; Middle Aged; Mouth Diseases; Pemphigus; Thal | 2011 |
Pemphigus vulgaris with involvement of the cervix treated using thalidomide therapy.
Topics: Azathioprine; Diagnosis, Differential; Drug Administration Schedule; Drug Therapy, Combination; Fema | 2004 |
[Beneficial effect of thalidomide in a case of Hailey-Hailey pemphigus. 1 years' trial].
Topics: Aged; Female; Humans; Pemphigus; Thalidomide; Time Factors | 1984 |