thalidomide has been researched along with Paralysis in 10 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Excerpt | Relevance | Reference |
---|---|---|
" Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes." | 1.32 | Reactions and their management. ( Ganapati, R; Pai, VV, 2004) |
"Cranial nerve palsy/paresis was only seen in HFM and thalidomide-induced malformations." | 1.30 | Teratological studies on craniofacial malformations. ( Jacobsson, C, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (80.00) | 18.7374 |
1990's | 1 (10.00) | 18.2507 |
2000's | 1 (10.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
COSTER, C | 1 |
D AVIGNON, M | 1 |
BARR, B | 1 |
Ganapati, R | 1 |
Pai, VV | 1 |
Jacobsson, C | 1 |
Gordon, GC | 1 |
Elsahy, NI | 1 |
Trieschmann, W | 1 |
Antia, NH | 1 |
Terrahe, K | 1 |
Homburger, F | 1 |
Bajusz, E | 1 |
10 other studies available for thalidomide and Paralysis
Article | Year |
---|---|
[Thalidomide neuropathy].
Topics: Humans; Neuritis; Paralysis; Paresthesia; Peripheral Nervous System Diseases; Thalidomide | 1963 |
EAR ABNORMALITIES AND CRANIAL NERVE PALSIES IN THALIDOMIDE CHILDREN.
Topics: Abnormalities, Drug-Induced; Child; Cranial Nerve Diseases; Cranial Nerves; Deafness; Ear Deformitie | 1964 |
Reactions and their management.
Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad | 2004 |
Teratological studies on craniofacial malformations.
Topics: Alkaline Phosphatase; Aminopropionitrile; Amniotic Fluid; Animals; Branchial Region; Cartilage; Clef | 1997 |
Thalidomide and cranial nerve abnormalities.
Topics: Abnormalities, Drug-Induced; Child; Cranial Nerves; Humans; Paralysis; Thalidomide | 1978 |
Moebius syndrome associated with the mother taking thalidomide during gestation. Case report.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Anxiety; Facial Expression; Fa | 1973 |
[Crocodile tears in thalidomide embryopathy].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Child; Female; Humans; Male; Paralysis; Reflex, Abnorma | 1973 |
The significance of nerve involvement in leprosy.
Topics: Biopsy; Cortisone; Humans; Leprosy; Neuritis; Paralysis; Peripheral Nerves; Sensation; Thalidomide | 1974 |
[Diagnosis of malformations of the ear and temporal bone].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos | 1972 |
New models of human disease in Syrian hamsters.
Topics: Adenoma; Adrenal Gland Neoplasms; Animals; Cardiomyopathies; Cricetinae; Cyclamates; Disease Models, | 1970 |