Page last updated: 2024-11-05

thalidomide and Paralysis

thalidomide has been researched along with Paralysis in 10 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)

Research Excerpts

ExcerptRelevanceReference
" Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes."1.32Reactions and their management. ( Ganapati, R; Pai, VV, 2004)
"Cranial nerve palsy/paresis was only seen in HFM and thalidomide-induced malformations."1.30Teratological studies on craniofacial malformations. ( Jacobsson, C, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
COSTER, C1
D AVIGNON, M1
BARR, B1
Ganapati, R1
Pai, VV1
Jacobsson, C1
Gordon, GC1
Elsahy, NI1
Trieschmann, W1
Antia, NH1
Terrahe, K1
Homburger, F1
Bajusz, E1

Other Studies

10 other studies available for thalidomide and Paralysis

ArticleYear
[Thalidomide neuropathy].
    Svenska lakartidningen, 1963, Feb-28, Volume: 60

    Topics: Humans; Neuritis; Paralysis; Paresthesia; Peripheral Nervous System Diseases; Thalidomide

1963
EAR ABNORMALITIES AND CRANIAL NERVE PALSIES IN THALIDOMIDE CHILDREN.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Abnormalities, Drug-Induced; Child; Cranial Nerve Diseases; Cranial Nerves; Deafness; Ear Deformitie

1964
Reactions and their management.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad

2004
Teratological studies on craniofacial malformations.
    Swedish dental journal. Supplement, 1997, Volume: 121

    Topics: Alkaline Phosphatase; Aminopropionitrile; Amniotic Fluid; Animals; Branchial Region; Cartilage; Clef

1997
Thalidomide and cranial nerve abnormalities.
    British medical journal, 1978, Jan-28, Volume: 1, Issue:6107

    Topics: Abnormalities, Drug-Induced; Child; Cranial Nerves; Humans; Paralysis; Thalidomide

1978
Moebius syndrome associated with the mother taking thalidomide during gestation. Case report.
    Plastic and reconstructive surgery, 1973, Volume: 51, Issue:1

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Anxiety; Facial Expression; Fa

1973
[Crocodile tears in thalidomide embryopathy].
    Klinische Monatsblatter fur Augenheilkunde, 1973, Volume: 162, Issue:4

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Child; Female; Humans; Male; Paralysis; Reflex, Abnorma

1973
The significance of nerve involvement in leprosy.
    Plastic and reconstructive surgery, 1974, Volume: 54, Issue:1

    Topics: Biopsy; Cortisone; Humans; Leprosy; Neuritis; Paralysis; Peripheral Nerves; Sensation; Thalidomide

1974
[Diagnosis of malformations of the ear and temporal bone].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:1

    Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos

1972
New models of human disease in Syrian hamsters.
    JAMA, 1970, Apr-27, Volume: 212, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Animals; Cardiomyopathies; Cricetinae; Cyclamates; Disease Models,

1970