thalidomide has been researched along with Papilledema in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Papilledema: Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-seven (67." | 1.46 | OCULAR MANIFESTATIONS AND TREATMENT OUTCOMES IN CHINESE PATIENTS WITH POEMS SYNDROME. ( Cai, H; Cai, QQ; Cao, XX; Dai, RP; Huang, XF; Li, J; Zhang, X; Zhou, DB, 2017) |
| "If patients have optic disc edema in both eyes with no intracranial space-occupying lesion, POEMS syndrome should be considered in differential diagnosis, regardless of age." | 1.40 | POEMS syndrome in a 20-year-old patient diagnosed following a complaint of reduced visual acuity. ( Doi, S; Hosogi, M; Hosokawa, M; Kawata, T; Kimura, S; Kondo, E; Morizane, Y; Shiode, Y; Shiraga, F, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokouchi, H | 2 |
| Baba, T | 2 |
| Misawa, S | 1 |
| Oshitari, T | 2 |
| Kuwabara, S | 1 |
| Yamamoto, S | 2 |
| Doi, S | 1 |
| Kimura, S | 1 |
| Morizane, Y | 1 |
| Hosogi, M | 1 |
| Hosokawa, M | 1 |
| Shiode, Y | 1 |
| Kawata, T | 1 |
| Kondo, E | 1 |
| Shiraga, F | 1 |
| Zhang, X | 1 |
| Cai, QQ | 1 |
| Huang, XF | 1 |
| Cao, XX | 1 |
| Cai, H | 1 |
| Zhou, DB | 1 |
| Dai, RP | 1 |
| Li, J | 1 |
4 other studies available for thalidomide and Papilledema
| Article | Year |
|---|---|
Correlation of changes in serum level of VEGF and peripapillary retinal thickness in patients with POEMS syndrome.
Topics: Adult; Aged; Angiogenesis Inhibitors; Female; Humans; Male; Middle Aged; Papilledema; POEMS Syndrome | 2020 |
POEMS syndrome in a 20-year-old patient diagnosed following a complaint of reduced visual acuity.
Topics: Adult; Central Serous Chorioretinopathy; Combined Modality Therapy; Dexamethasone; Drug Therapy, Com | 2014 |
Thalidomide reduces choroidal thickness and optic disc edema in a patient with POEMS syndrome.
Topics: Angiogenesis Inhibitors; Choroid Diseases; Female; Humans; Middle Aged; Papilledema; POEMS Syndrome; | 2015 |
OCULAR MANIFESTATIONS AND TREATMENT OUTCOMES IN CHINESE PATIENTS WITH POEMS SYNDROME.
Topics: Adult; Aged; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Dexamethasone; Female; Humans; Lenal | 2017 |