Page last updated: 2024-11-05

thalidomide and Pancytopenia

thalidomide has been researched along with Pancytopenia in 5 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.

Research Excerpts

ExcerptRelevanceReference
"Lenalidomide is an important medication used in induction therapy for MM and is also used for maintenance therapy for standard risk patients."5.72Three Cases of Lenalidomide Therapy for Multiple Myeloma and Subsequent Development of Secondary B-ALL. ( Asawa, P; Chahine, Z; Lister, J; Sadashiv, S; Samhouri, Y; Vusqa, UT, 2022)
"A man in his late 60s who had received the first cycle of a chemotherapeutic regimen of ixazomib, lenalidomide, and dexamethasone for multiple myeloma presented to the dermatologic clinic with a 10-day history of fever and tender lesions on the neck and trunk."4.31Fever, Pancytopenia, and Tender Erythematous Plaques in a Patient With Multiple Myeloma. ( Katayama, S; Ota, M; Yamaga, M, 2023)
"Lenalidomide is an important medication used in induction therapy for MM and is also used for maintenance therapy for standard risk patients."1.72Three Cases of Lenalidomide Therapy for Multiple Myeloma and Subsequent Development of Secondary B-ALL. ( Asawa, P; Chahine, Z; Lister, J; Sadashiv, S; Samhouri, Y; Vusqa, UT, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Vusqa, UT1
Chahine, Z1
Asawa, P1
Sadashiv, S1
Samhouri, Y1
Lister, J1
Yamaga, M1
Katayama, S1
Ota, M1
Rao, K1
Murthy, H1
Muralidhar, NS1
Rani, PK1
Sukrisman, L1
Mulansari, NA1
Sudoyo, AW1
Mesa, RA1
Steensma, DP1
Pardanani, A1
Li, CY1
Elliott, M1
Kaufmann, SH1
Wiseman, G1
Gray, LA1
Schroeder, G1
Reeder, T1
Zeldis, JB1
Tefferi, A1

Trials

1 trial available for thalidomide and Pancytopenia

ArticleYear
A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia.
    Blood, 2003, Apr-01, Volume: 101, Issue:7

    Topics: Adrenal Cortex Hormones; Aged; Anemia; Angiogenesis Inhibitors; Antineoplastic Agents, Hormonal; Ant

2003

Other Studies

4 other studies available for thalidomide and Pancytopenia

ArticleYear
Three Cases of Lenalidomide Therapy for Multiple Myeloma and Subsequent Development of Secondary B-ALL.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:5

    Topics: Aged; Humans; Lenalidomide; Multiple Myeloma; Neoplasm Recurrence, Local; Pancytopenia; Thalidomide

2022
Fever, Pancytopenia, and Tender Erythematous Plaques in a Patient With Multiple Myeloma.
    JAMA dermatology, 2023, 07-01, Volume: 159, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Erythema; Humans; Lenalidomide; Multi

2023
Multiple myeloma masquerading as diabetic macular oedema.
    BMJ case reports, 2018, Apr-17, Volume: 2018

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Large-Core Needle; Bone Marrow; Cycl

2018
A case with pancytopenia: the role of cytomorphology.
    Acta medica Indonesiana, 2013, Volume: 45, Issue:1

    Topics: Bone Marrow; Cytodiagnosis; Female; Humans; Immunosuppressive Agents; Middle Aged; Myelodysplastic S

2013