thalidomide has been researched along with Orphan Diseases in 9 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Scleromyxedema is a rare idiopathic fibromucinous disorder characterized by a generalized papular and sclerodermoid cutaneous eruption." | 1.72 | Case report: Scleromyxedema associated with a monoclonal gammapathy: Successful treatment with intravenous immunoglobulins. ( Chen, QY; Wang, SS; Xiang, LH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Khurana, A | 1 |
| Savitha, B | 1 |
| Wang, SS | 1 |
| Chen, QY | 1 |
| Xiang, LH | 1 |
| Mouhieddine, TH | 1 |
| Barlogie, B | 1 |
| Teruya-Feldstein, J | 1 |
| Khandkar, C | 1 |
| Vaidya, K | 1 |
| Penglase, R | 1 |
| Cai, K | 1 |
| Shin, JS | 1 |
| Hunyor, I | 1 |
| Keech, A | 1 |
| McGill, N | 1 |
| Rani, S | 1 |
| Gupta, A | 1 |
| Bhardwaj, M | 1 |
| Ravinet, A | 1 |
| Bay, JO | 1 |
| Tournilhac, O | 1 |
| Jia, J | 1 |
| Tian, Q | 1 |
| Zhang, H | 1 |
| Zheng, Y | 1 |
| Meier, F | 1 |
| Berner, D | 1 |
| Scherwitz, C | 1 |
| Rassner, G | 1 |
| Metzler, G | 1 |
| McGowan, N | 1 |
2 reviews available for thalidomide and Orphan Diseases
| Article | Year |
|---|---|
[Plasma cell leukemia].
Topics: Aged; Antineoplastic Agents; Biomedical Research; Boronic Acids; Bortezomib; Female; Hematopoietic S | 2014 |
What's wrong with this patient? Primary systemic amyloidosis.
Topics: Aged; Amyloidosis; Anti-Inflammatory Agents; Dexamethasone; Diagnosis, Differential; Disease Progres | 2006 |
7 other studies available for thalidomide and Orphan Diseases
| Article | Year |
|---|---|
Refractory angiolymphoid hyperplasia with eosinophilia: Complete resolution with low dose thalidomide.
Topics: Angiolymphoid Hyperplasia with Eosinophilia; Head; Hemangioma; Humans; Rare Diseases; Thalidomide | 2022 |
Case report: Scleromyxedema associated with a monoclonal gammapathy: Successful treatment with intravenous immunoglobulins.
Topics: Exanthema; Female; Humans; Immunoglobulins, Intravenous; Middle Aged; Paraproteinemias; Rare Disease | 2022 |
Hemophagocytic relapsed intramedullary plasmacytoma.
Topics: Adult; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bo | 2020 |
Rare case of infiltrative cardiomyopathy secondary to scleromyxoedema.
Topics: Adult; Cardiomyopathies; Female; Humans; Immunoglobulins, Intravenous; Magnetic Resonance Imaging; P | 2020 |
Epidermolysis bullosa pruriginosa: A rare entity which responded well to thalidomide.
Topics: Adult; Biopsy; Epidermolysis Bullosa Dystrophica; Humans; Immunosuppressive Agents; Male; Rare Disea | 2019 |
An unusual case of multiple cutaneous Rosai-Dorfman disease involving two separate parts of the body.
Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Arm; Biopsy, Needle; Breast; | 2017 |
[An unusual case of pyoderma gangrenosum with necrotizing granulomatous dermatitis].
Topics: Dermatitis; Granuloma; Humans; Male; Middle Aged; Pyoderma Gangrenosum; Rare Diseases; Thalidomide; | 2003 |