thalidomide has been researched along with Neurodevelopmental Disorders in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Neurodevelopmental Disorders: These are a group of conditions with onset in the developmental period. The disorders typically manifest early in development, often before the child enters grade school, and are characterized by developmental deficits that produce impairments of personal, social, academic, or occupational functioning. (From DSM-5).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kikegawa, M | 1 |
| Qin, XY | 1 |
| Ito, T | 1 |
| Nishikawa, H | 1 |
| Nansai, H | 1 |
| Sone, H | 1 |
| Zieminska, E | 1 |
| Lenart, J | 1 |
| Lazarewicz, JW | 1 |
2 other studies available for thalidomide and Neurodevelopmental Disorders
| Article | Year |
|---|---|
Early Transcriptomic Changes upon Thalidomide Exposure Influence the Later Neuronal Development in Human Embryonic Stem Cell-Derived Spheres.
Topics: Cell Differentiation; Cell Line; Gene Expression Regulation, Developmental; Human Embryonic Stem Cel | 2020 |
Select putative neurodevelopmental toxins modify SNAP-25 expression in primary cultures of rat cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; Exocytosis; Gene Expression Regulation; Metal Nanoparticles; N | 2016 |