thalidomide has been researched along with Neurodermatitis in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Neurodermatitis: An extremely variable eczematous skin disease that is presumed to be a response to prolonged vigorous scratching, rubbing, or pinching to relieve intense pruritus. It varies in intensity, severity, course, and morphologic expression in different individuals. Neurodermatitis is believed by some to be psychogenic. The circumscribed or localized form is often referred to as lichen simplex chronicus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-two patients suffering from prurigo nodularis were treated with thalidomide 50-300 mg daily for an average of 12 months (two weeks to five years), following a special arrangement between the Danish Government and the producer Grünenthal GMBH, by which the Government took full economical responsibility for any claims related to the treatment." | 7.68 | [Thalidomide treatment of prurigo nodularis]. ( Jøhnke, H; Zachariae, H, 1993) |
| "Thalidomide was thought to be the cause of hypercoagulability and coronary spasm, so it was ceased immediately." | 5.42 | Myocardial infarction, symptomatic third degree atrioventricular block and pulmonary embolism caused by thalidomide: a case report. ( Jin, X; Yang, J; Zhang, S, 2015) |
| "Twenty-two patients suffering from prurigo nodularis were treated with thalidomide 50-300 mg daily for an average of 12 months (two weeks to five years), following a special arrangement between the Danish Government and the producer Grünenthal GMBH, by which the Government took full economical responsibility for any claims related to the treatment." | 3.68 | [Thalidomide treatment of prurigo nodularis]. ( Jøhnke, H; Zachariae, H, 1993) |
| "Thalidomide was thought to be the cause of hypercoagulability and coronary spasm, so it was ceased immediately." | 1.42 | Myocardial infarction, symptomatic third degree atrioventricular block and pulmonary embolism caused by thalidomide: a case report. ( Jin, X; Yang, J; Zhang, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 2 |
| Yang, J | 1 |
| Jin, X | 1 |
| Jøhnke, H | 1 |
| Zachariae, H | 1 |
2 other studies available for thalidomide and Neurodermatitis
| Article | Year |
|---|---|
Myocardial infarction, symptomatic third degree atrioventricular block and pulmonary embolism caused by thalidomide: a case report.
Topics: Anticoagulants; Atrioventricular Block; Cardiac Pacing, Artificial; Coronary Angiography; Dermatolog | 2015 |
[Thalidomide treatment of prurigo nodularis].
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neurodermatitis; Prurigo; Thalido | 1993 |