thalidomide has been researched along with Neuritis in 21 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Neuritis: A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has been reported to be an effective agent for treatment of chronic graft-versus-host disease (CGVHD)." | 9.08 | Thalidomide as salvage therapy for chronic graft-versus-host disease. ( Blume, KG; Chao, N; Forman, SJ; Kashyap, A; Long, GD; Margolin, K; Molina, A; Nademanee, A; Negrin, RS; Niland, JC; O'Donnell, MR; Parker, PM; Planas, I; Schmidt, GM; Smith, EP; Snyder, DS; Somlo, G; Spielberger, R; Stein, AS; Stepan, DE; Wilsman, K; Zwingenberger, K, 1995) |
| "Cases of neuritis responded much more satisfactorily and there was no change in the muscle deficity before or after treatment with thalidomide." | 5.26 | Treatment with thalidomide in steroid dependency and neuritis. ( Theophilus, S, 1980) |
| "Thalidomide has been reported to be an effective agent for treatment of chronic graft-versus-host disease (CGVHD)." | 5.08 | Thalidomide as salvage therapy for chronic graft-versus-host disease. ( Blume, KG; Chao, N; Forman, SJ; Kashyap, A; Long, GD; Margolin, K; Molina, A; Nademanee, A; Negrin, RS; Niland, JC; O'Donnell, MR; Parker, PM; Planas, I; Schmidt, GM; Smith, EP; Snyder, DS; Somlo, G; Spielberger, R; Stein, AS; Stepan, DE; Wilsman, K; Zwingenberger, K, 1995) |
| "Based on present publications we review indications of the therapy of dermatoses with thalidomide as well as possible mechanisms of action and side effects of this drug." | 3.66 | [Thalidomide in dermatology]. ( Hunziker, T; Krebs, A, 1983) |
| " Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes." | 1.32 | Reactions and their management. ( Ganapati, R; Pai, VV, 2004) |
| "In experiment 1, rats with the neuritis but not those with the myositis developed neuropathic pain symptoms." | 1.31 | A neuroimmune interaction in painful peripheral neuropathy. ( Bennett, GJ, 2000) |
| "Cases of neuritis responded much more satisfactorily and there was no change in the muscle deficity before or after treatment with thalidomide." | 1.26 | Treatment with thalidomide in steroid dependency and neuritis. ( Theophilus, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leon, KE | 1 |
| Salinas, JL | 1 |
| McDonald, RW | 1 |
| Sheth, AN | 1 |
| Fairley, JK | 1 |
| Silverman, WA | 1 |
| FRENKEL, H | 1 |
| SCHEID, W | 1 |
| WIECK, HH | 1 |
| STAMMLER, A | 1 |
| KLADETZKY, A | 1 |
| GIBBELS, E | 1 |
| COSTER, C | 1 |
| SKRE, H | 1 |
| ARNVIG, J | 1 |
| KELSEY, FO | 1 |
| MICHAELIS, R | 1 |
| TARNOW, G | 1 |
| HULTSCH, EG | 1 |
| HARTMANN, J | 1 |
| Ganapati, R | 1 |
| Pai, VV | 1 |
| Umapathi, T | 1 |
| Chaudhry, V | 1 |
| Hunziker, T | 1 |
| Krebs, A | 1 |
| Theophilus, S | 1 |
| Parker, PM | 1 |
| Chao, N | 1 |
| Nademanee, A | 1 |
| O'Donnell, MR | 1 |
| Schmidt, GM | 1 |
| Snyder, DS | 1 |
| Stein, AS | 1 |
| Smith, EP | 1 |
| Molina, A | 1 |
| Stepan, DE | 1 |
| Kashyap, A | 1 |
| Planas, I | 1 |
| Spielberger, R | 1 |
| Somlo, G | 1 |
| Margolin, K | 1 |
| Zwingenberger, K | 1 |
| Wilsman, K | 1 |
| Negrin, RS | 1 |
| Long, GD | 1 |
| Niland, JC | 1 |
| Blume, KG | 1 |
| Forman, SJ | 1 |
| Bennett, GJ | 1 |
| Revuz, J | 1 |
| Thomas, PK | 1 |
| Sabin, TD | 1 |
| Antia, NH | 1 |
| Belda, W | 1 |
| Manzoli, S | 1 |
| Jordy, CF | 1 |
3 reviews available for thalidomide and Neuritis
| Article | Year |
|---|---|
Toxic neuropathy.
Topics: Animals; Boronic Acids; Bortezomib; Clinical Trials as Topic; Epothilones; Genetic Therapy; Humans; | 2005 |
[Current use of thalidomide].
Topics: Abnormalities, Drug-Induced; Behcet Syndrome; Dose-Response Relationship, Drug; Humans; Leprosy, Lep | 1990 |
The morphological basis for alterations in nerve conduction in peripheral neuropathy.
Topics: Amyloidosis; Animals; Axons; Beriberi; Cresols; Demyelinating Diseases; Diabetic Neuropathies; Diffu | 1971 |
1 trial available for thalidomide and Neuritis
| Article | Year |
|---|---|
Thalidomide as salvage therapy for chronic graft-versus-host disease.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Chronic Disease; Constipation; Cyclosporine; | 1995 |
17 other studies available for thalidomide and Neuritis
| Article | Year |
|---|---|
Complex Type 2 Reactions in Three Patients with Hansen's Disease from a Southern United States Clinic.
Topics: Adult; Aged; Anti-Inflammatory Agents; Asia, Southeastern; Bangladesh; Erythema Nodosum; Female; Geo | 2015 |
The schizophrenic career of a "monster drug".
Topics: Animals; Drug Evaluation, Preclinical; Germany, West; History, 20th Century; Humans; Hypnotics and S | 2002 |
[Contergan--side effects. Central nervous system manifestations and polyneuritic symptoms in long-term medication with N-phthalyl glutamic acid imide].
Topics: Glutamic Acid; Humans; Hypnotics and Sedatives; Imides; Nervous System Physiological Phenomena; Neur | 1961 |
[Polyneuritic syndrome after prolonged thalidomide medication].
Topics: Hypnotics and Sedatives; Neuritis; Syndrome; Thalidomide | 1961 |
[Thalidomide neuropathy].
Topics: Humans; Neuritis; Paralysis; Paresthesia; Peripheral Nervous System Diseases; Thalidomide | 1963 |
[THALIDOMIDE POLYNEURITIS: A FORM OF RIBOFLAVIN AVITAMINOSIS?].
Topics: Avitaminosis; Dermatology; Drug Hypersensitivity; Edema; Folic Acid; Geriatrics; Headache; Neuritis; | 1963 |
TRANSITORY DECREASE OF HEARING AFTER LUMBAR PUNCTURE. A PERSONAL EXPERIENCE WHICH THROWS SOME LIGHT ON THE FUNCTION OF THE AQUEDUCT OF THE COCHLEAE.
Topics: Cochlea; Ear, Inner; Hearing; Hearing Disorders; Humans; Intracranial Pressure; Neuritis; Spinal Pun | 1963 |
PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY 1960-1961.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Geriatrics; Germany; Germany, | 1964 |
[NEUROLOGICAL DISEASES AS SEQUELS TO CONTERGAN USE IN DISORDERS OF INTESTINAL RESORPTION].
Topics: Central Nervous System Diseases; Gastric Acidity Determination; Gastritis; Intestinal Diseases; Neur | 1963 |
[Nil nocere. Thalidomide (Contergan) polyneuritis].
Topics: Hypnotics and Sedatives; Neuritis; Thalidomide | 1961 |
Reactions and their management.
Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad | 2004 |
[Thalidomide in dermatology].
Topics: Animals; Female; Guinea Pigs; Humans; Immunity; Leprosy; Lupus Erythematosus, Discoid; Male; Mice; N | 1983 |
Treatment with thalidomide in steroid dependency and neuritis.
Topics: Adrenal Cortex Hormones; Erythema Nodosum; Humans; Leprosy; Male; Neuritis; Recurrence; Thalidomide | 1980 |
A neuroimmune interaction in painful peripheral neuropathy.
Topics: Animals; Constriction, Pathologic; Cyclosporine; Dose-Response Relationship, Drug; Immunosuppressive | 2000 |
Letter: Thalidomine neuropathy and leprous neuritis.
Topics: Diagnosis, Differential; Humans; Hypesthesia; Leprosy; Mycobacterium leprae; Neuritis; Peripheral Ne | 1974 |
The significance of nerve involvement in leprosy.
Topics: Biopsy; Cortisone; Humans; Leprosy; Neuritis; Paralysis; Peripheral Nerves; Sensation; Thalidomide | 1974 |
[Thalidomide in the control of pain in leprotic neuritis].
Topics: Female; Humans; Leprosy; Male; Neuralgia; Neuritis; Pain; Thalidomide | 1966 |