thalidomide has been researched along with Nephritis in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Nephritis: Inflammation of any part of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide treatment also significantly reduced tissue levels of the proinflammatory cytokines, MDA, MPO, and NO and increased anti-inflammatory cytokine IL-10." | 5.42 | Thalidomide ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in an experimental model. ( Amirshahrokhi, K; Khalili, AR, 2015) |
| "Treatment with thalidomide markedly stimulated the phosphorylation of AMPKα." | 1.48 | Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway. ( Li, R; Wang, B; Wang, Y; Yang, Y; Zhang, H, 2018) |
| "Thalidomide treatment also significantly reduced tissue levels of the proinflammatory cytokines, MDA, MPO, and NO and increased anti-inflammatory cytokine IL-10." | 1.42 | Thalidomide ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in an experimental model. ( Amirshahrokhi, K; Khalili, AR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Yang, Y | 1 |
| Wang, Y | 1 |
| Wang, B | 1 |
| Li, R | 1 |
| Scharpfenecker, M | 1 |
| Floot, B | 1 |
| Russell, NS | 1 |
| Coppes, RP | 1 |
| Stewart, FA | 1 |
| Amirshahrokhi, K | 1 |
| Khalili, AR | 1 |
3 other studies available for thalidomide and Nephritis
| Article | Year |
|---|---|
Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cytokines; Cytoprotection; Diabete | 2018 |
Thalidomide ameliorates inflammation and vascular injury but aggravates tubular damage in the irradiated mouse kidney.
Topics: Angiogenesis Modulating Agents; Animals; Anti-Inflammatory Agents; Female; Fibrosis; Genes, sis; Glo | 2014 |
Thalidomide ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in an experimental model.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Blood Urea Nitrogen; | 2015 |