thalidomide has been researched along with Nail Abnormalities in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thalidomide was taken in the sensitive period of the pregnancy by the father's mother." | 4.80 | Unilateral terminal aphalangia in father and daughter--exogenous or genetic cause? ( Kunze, J; Neumann, L; Pelz, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neumann, L | 1 |
| Pelz, J | 1 |
| Kunze, J | 1 |
1 review available for thalidomide and Nail Abnormalities
| Article | Year |
|---|---|
Unilateral terminal aphalangia in father and daughter--exogenous or genetic cause?
Topics: Adult; Fathers; Female; Fingers; Forearm; Genes, Dominant; Hand Deformities, Congenital; Humans; Inf | 1998 |