thalidomide has been researched along with Myxedema in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Myxedema: A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Scleromyxedema is a generalized, papular, and sclerodermoid form of lichen myxedematosus associated with monoclonal gammopathy and systemic changes." | 5.32 | Treatment of recalcitrant scleromyxedema with thalidomide in 3 patients. ( Cocuroccia, B; Girolomoni, G; Gisondi, P; Gubinelli, E; Jorizzo, JL; Sansbury, JC, 2004) |
| "Scleromyxedema is a generalized, papular, and sclerodermoid form of lichen myxedematosus associated with monoclonal gammopathy and systemic changes." | 1.32 | Treatment of recalcitrant scleromyxedema with thalidomide in 3 patients. ( Cocuroccia, B; Girolomoni, G; Gisondi, P; Gubinelli, E; Jorizzo, JL; Sansbury, JC, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caradonna, S | 1 |
| Jacobe, H | 1 |
| Sansbury, JC | 1 |
| Cocuroccia, B | 1 |
| Jorizzo, JL | 1 |
| Gubinelli, E | 1 |
| Gisondi, P | 1 |
| Girolomoni, G | 1 |
2 other studies available for thalidomide and Myxedema
| Article | Year |
|---|---|
Thalidomide as a potential treatment for scleromyxedema.
Topics: Administration, Oral; Adult; Diagnosis, Differential; Facial Dermatoses; Female; Humans; Immunosuppr | 2004 |
Treatment of recalcitrant scleromyxedema with thalidomide in 3 patients.
Topics: Aged; Female; Humans; Lichenoid Eruptions; Male; Middle Aged; Myxedema; Paraproteinemias; Scleroderm | 2004 |